Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889006688> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2889006688 abstract "Objectives: To detect Leishmania species in human patients, animal reservoirs and Phlebotomus sandflies in Waziristan, Pakistan. Methods: Tissue smears and aspirates from 448 cutaneous leishmaniasis (CL) suspected patients were analyzed. To sort out role of the reservoir hosts, skin scrapings, spleen and liver samples from 104 rodents were collected. Furthermore, buffy coat samples were obtained from 60 domestic animals. Sandflies were also trapped. All human, animals and sandfly samples were tested by microscopy, kinetoplastic PCR and internal transcribed spacer 1 (ITS1) PCR followed by restriction fragment length polymorphism for detection of Leishmania species. Results: An overall prevalence of 3.83% and 5.21% through microscopy and ITS1 PCR respectively was found. However, the statistically non-significant correlation was found between area, gender, and number of lesions. The presence of rodents, sandflies, domestic animals and internally displaced people increased the risk of CL. Using ITS1-PCR-RFLP, Leishmania tropica (L. tropica) was confirmed in 106 samples while 25 of the isolates were diagnosed as Leishmania major (L. major). Similarly, 3/104 rodents were positive for L. major and 14 pools of DNA samples containing Phlebotomus sergenti sandflies were positive for L. tropica. None of samples from domestic animals were positive for leishmaniasis. Conclusions: In the present study, L. tropica and L. major are found to be the main causative agents of CL in study area. Movement of internally displaced people from CL endemic areas presents a risk for nearby CL free areas. To the best of our knowledge, we report for the first time L. major infection in rodents (Rattus rattus) and L. tropica in Phlebotomus sergenti sandflies trapped in Waziristan, Pakistan." @default.
- W2889006688 created "2018-09-07" @default.
- W2889006688 creator A5003629836 @default.
- W2889006688 creator A5008598468 @default.
- W2889006688 creator A5023486713 @default.
- W2889006688 creator A5025803003 @default.
- W2889006688 creator A5030138075 @default.
- W2889006688 creator A5031831371 @default.
- W2889006688 creator A5040127910 @default.
- W2889006688 creator A5044266433 @default.
- W2889006688 creator A5057982822 @default.
- W2889006688 creator A5063663319 @default.
- W2889006688 creator A5065408600 @default.
- W2889006688 creator A5066441206 @default.
- W2889006688 creator A5073457866 @default.
- W2889006688 creator A5082776927 @default.
- W2889006688 creator A5088163188 @default.
- W2889006688 date "2018-01-01" @default.
- W2889006688 modified "2023-10-18" @default.
- W2889006688 title "Molecular detection of Leishmania species in human and animals from cutaneous leishmaniasis endemic areas of Waziristan, Khyber Pakhtunkhwa, Pakistan" @default.
- W2889006688 doi "https://doi.org/10.4103/1995-7645.240086" @default.
- W2889006688 hasPublicationYear "2018" @default.
- W2889006688 type Work @default.
- W2889006688 sameAs 2889006688 @default.
- W2889006688 citedByCount "1" @default.
- W2889006688 countsByYear W28890066882020 @default.
- W2889006688 crossrefType "journal-article" @default.
- W2889006688 hasAuthorship W2889006688A5003629836 @default.
- W2889006688 hasAuthorship W2889006688A5008598468 @default.
- W2889006688 hasAuthorship W2889006688A5023486713 @default.
- W2889006688 hasAuthorship W2889006688A5025803003 @default.
- W2889006688 hasAuthorship W2889006688A5030138075 @default.
- W2889006688 hasAuthorship W2889006688A5031831371 @default.
- W2889006688 hasAuthorship W2889006688A5040127910 @default.
- W2889006688 hasAuthorship W2889006688A5044266433 @default.
- W2889006688 hasAuthorship W2889006688A5057982822 @default.
- W2889006688 hasAuthorship W2889006688A5063663319 @default.
- W2889006688 hasAuthorship W2889006688A5065408600 @default.
- W2889006688 hasAuthorship W2889006688A5066441206 @default.
- W2889006688 hasAuthorship W2889006688A5073457866 @default.
- W2889006688 hasAuthorship W2889006688A5082776927 @default.
- W2889006688 hasAuthorship W2889006688A5088163188 @default.
- W2889006688 hasBestOaLocation W28890066881 @default.
- W2889006688 hasConcept C136764020 @default.
- W2889006688 hasConcept C144024400 @default.
- W2889006688 hasConcept C203014093 @default.
- W2889006688 hasConcept C205649164 @default.
- W2889006688 hasConcept C2776555147 @default.
- W2889006688 hasConcept C2778702967 @default.
- W2889006688 hasConcept C2781092759 @default.
- W2889006688 hasConcept C3020075751 @default.
- W2889006688 hasConcept C41008148 @default.
- W2889006688 hasConcept C42972112 @default.
- W2889006688 hasConcept C45355965 @default.
- W2889006688 hasConcept C556039675 @default.
- W2889006688 hasConcept C71924100 @default.
- W2889006688 hasConcept C71928629 @default.
- W2889006688 hasConcept C86803240 @default.
- W2889006688 hasConceptScore W2889006688C136764020 @default.
- W2889006688 hasConceptScore W2889006688C144024400 @default.
- W2889006688 hasConceptScore W2889006688C203014093 @default.
- W2889006688 hasConceptScore W2889006688C205649164 @default.
- W2889006688 hasConceptScore W2889006688C2776555147 @default.
- W2889006688 hasConceptScore W2889006688C2778702967 @default.
- W2889006688 hasConceptScore W2889006688C2781092759 @default.
- W2889006688 hasConceptScore W2889006688C3020075751 @default.
- W2889006688 hasConceptScore W2889006688C41008148 @default.
- W2889006688 hasConceptScore W2889006688C42972112 @default.
- W2889006688 hasConceptScore W2889006688C45355965 @default.
- W2889006688 hasConceptScore W2889006688C556039675 @default.
- W2889006688 hasConceptScore W2889006688C71924100 @default.
- W2889006688 hasConceptScore W2889006688C71928629 @default.
- W2889006688 hasConceptScore W2889006688C86803240 @default.
- W2889006688 hasLocation W28890066881 @default.
- W2889006688 hasLocation W28890066882 @default.
- W2889006688 hasOpenAccess W2889006688 @default.
- W2889006688 hasPrimaryLocation W28890066881 @default.
- W2889006688 hasRelatedWork W1510204305 @default.
- W2889006688 hasRelatedWork W1874423939 @default.
- W2889006688 hasRelatedWork W1991543232 @default.
- W2889006688 hasRelatedWork W2119160589 @default.
- W2889006688 hasRelatedWork W2155023133 @default.
- W2889006688 hasRelatedWork W2186179198 @default.
- W2889006688 hasRelatedWork W2361189616 @default.
- W2889006688 hasRelatedWork W2737677783 @default.
- W2889006688 hasRelatedWork W2889006688 @default.
- W2889006688 hasRelatedWork W4224034434 @default.
- W2889006688 isParatext "false" @default.
- W2889006688 isRetracted "false" @default.
- W2889006688 magId "2889006688" @default.
- W2889006688 workType "article" @default.