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- W2889039834 abstract "N-halosuccinimides (NXSs) are well-known to be convenient, easily manipulable and low-priced halogenation reagents in organic synthesis. In the present work, N-bromosuccinimide (NBS) has been promoted as the most efficient and selective catalyst among the NXSs in the reaction of direct esterification of aryl and alkyl carboxylic acids. Comprehensive esterification of substituted benzoic acids, mono-, di- and tri-carboxy alkyl derivatives has been performed under neat reaction conditions. The method is metal-free, air- and moisture-tolerant, allowing for a simple synthetic and isolation procedure as well as the large-scale synthesis of aromatic and alkyl esters with yields up to 100%. Protocol for the recycling of the catalyst has been proposed." @default.
- W2889039834 created "2018-09-07" @default.
- W2889039834 creator A5026741703 @default.
- W2889039834 creator A5028820087 @default.
- W2889039834 creator A5076836054 @default.
- W2889039834 date "2018-09-02" @default.
- W2889039834 modified "2023-10-18" @default.
- W2889039834 title "Esterification of Aryl/Alkyl Acids Catalysed by N-bromosuccinimide under Mild Reaction Conditions" @default.
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- W2889039834 doi "https://doi.org/10.3390/molecules23092235" @default.
- W2889039834 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6225170" @default.
- W2889039834 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30200547" @default.
- W2889039834 hasPublicationYear "2018" @default.
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