FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889372758> ?p ?o ?g. }

• W2889372758 endingPage "49" @default.
• W2889372758 startingPage "45" @default.
• W2889372758 abstract "Although immunosuppressive therapies have made organ transplantation a common medical procedure worldwide, chronic toxicity is a major issue of long-term treatment. One method to improve such therapies is the application of immunomodulatory agents from parasites, such as Hypoderma lineatum (Diptera: Oestridae). Hypodermin C (HC) is an enzyme secreted by H. lineatum larvae, and our previous study showed that recombinant HC could degrade guinea pig C3 and inhibit the complement pathway in vitro, suggesting potential activity for inhibiting transplant rejection. However, such properties have not been fully demonstrated in vivo. In this study, we investigated the impact of HC on a fully MHC-mismatched, life-sustaining, murine model of kidney allograft rejection using B6 donors and BABL/c (HC transgenic or wild-type) recipients. Kidney grafts were analyzed by histology, immunohistochemistry and western blotting. The results suggested that HC could effectively inhibit kidney allograft rejection. These findings suggest HC is a promising strategy to improve the survival of human implants." @default.
• W2889372758 created "2018-09-07" @default.
• W2889372758 creator A5003642180 @default.
• W2889372758 creator A5028718810 @default.
• W2889372758 creator A5054417040 @default.
• W2889372758 creator A5059972807 @default.
• W2889372758 creator A5063861565 @default.
• W2889372758 date "2018-12-01" @default.
• W2889372758 modified "2023-10-17" @default.
• W2889372758 title "Hypodermin C improves the survival of kidney allografts" @default.
• W2889372758 cites W1520306176 @default.
• W2889372758 cites W1931016989 @default.
• W2889372758 cites W1971085682 @default.
• W2889372758 cites W1976178369 @default.
• W2889372758 cites W1977043587 @default.
• W2889372758 cites W1982302643 @default.
• W2889372758 cites W1987712040 @default.
• W2889372758 cites W2036400456 @default.
• W2889372758 cites W2050136837 @default.
• W2889372758 cites W2051872988 @default.
• W2889372758 cites W2061425666 @default.
• W2889372758 cites W2072285198 @default.
• W2889372758 cites W2083299744 @default.
• W2889372758 cites W2083967424 @default.
• W2889372758 cites W2088735618 @default.
• W2889372758 cites W2091184847 @default.
• W2889372758 cites W2115838504 @default.
• W2889372758 cites W2125281388 @default.
• W2889372758 cites W2128864185 @default.
• W2889372758 cites W4211113303 @default.
• W2889372758 doi "https://doi.org/10.1016/j.trim.2018.09.001" @default.
• W2889372758 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30184470" @default.
• W2889372758 hasPublicationYear "2018" @default.
• W2889372758 type Work @default.
• W2889372758 sameAs 2889372758 @default.
• W2889372758 citedByCount "2" @default.
• W2889372758 countsByYear W28893727582020 @default.
• W2889372758 countsByYear W28893727582021 @default.
• W2889372758 crossrefType "journal-article" @default.
• W2889372758 hasAuthorship W2889372758A5003642180 @default.
• W2889372758 hasAuthorship W2889372758A5028718810 @default.
• W2889372758 hasAuthorship W2889372758A5054417040 @default.
• W2889372758 hasAuthorship W2889372758A5059972807 @default.
• W2889372758 hasAuthorship W2889372758A5063861565 @default.
• W2889372758 hasConcept C104317684 @default.
• W2889372758 hasConcept C126322002 @default.
• W2889372758 hasConcept C142724271 @default.
• W2889372758 hasConcept C150903083 @default.
• W2889372758 hasConcept C168444539 @default.
• W2889372758 hasConcept C202751555 @default.
• W2889372758 hasConcept C203014093 @default.
• W2889372758 hasConcept C204232928 @default.
• W2889372758 hasConcept C207001950 @default.
• W2889372758 hasConcept C2778815084 @default.
• W2889372758 hasConcept C2780091579 @default.
• W2889372758 hasConcept C2780303639 @default.
• W2889372758 hasConcept C2911091166 @default.
• W2889372758 hasConcept C55493867 @default.
• W2889372758 hasConcept C57742111 @default.
• W2889372758 hasConcept C71924100 @default.
• W2889372758 hasConcept C85265743 @default.
• W2889372758 hasConcept C86803240 @default.
• W2889372758 hasConceptScore W2889372758C104317684 @default.
• W2889372758 hasConceptScore W2889372758C126322002 @default.
• W2889372758 hasConceptScore W2889372758C142724271 @default.
• W2889372758 hasConceptScore W2889372758C150903083 @default.
• W2889372758 hasConceptScore W2889372758C168444539 @default.
• W2889372758 hasConceptScore W2889372758C202751555 @default.
• W2889372758 hasConceptScore W2889372758C203014093 @default.
• W2889372758 hasConceptScore W2889372758C204232928 @default.
• W2889372758 hasConceptScore W2889372758C207001950 @default.
• W2889372758 hasConceptScore W2889372758C2778815084 @default.
• W2889372758 hasConceptScore W2889372758C2780091579 @default.
• W2889372758 hasConceptScore W2889372758C2780303639 @default.
• W2889372758 hasConceptScore W2889372758C2911091166 @default.
• W2889372758 hasConceptScore W2889372758C55493867 @default.
• W2889372758 hasConceptScore W2889372758C57742111 @default.
• W2889372758 hasConceptScore W2889372758C71924100 @default.
• W2889372758 hasConceptScore W2889372758C85265743 @default.
• W2889372758 hasConceptScore W2889372758C86803240 @default.
• W2889372758 hasLocation W28893727581 @default.
• W2889372758 hasLocation W28893727582 @default.
• W2889372758 hasOpenAccess W2889372758 @default.
• W2889372758 hasPrimaryLocation W28893727581 @default.
• W2889372758 hasRelatedWork W1488009717 @default.
• W2889372758 hasRelatedWork W1966686390 @default.
• W2889372758 hasRelatedWork W1983530931 @default.
• W2889372758 hasRelatedWork W2011390696 @default.
• W2889372758 hasRelatedWork W2061829983 @default.
• W2889372758 hasRelatedWork W2064231441 @default.
• W2889372758 hasRelatedWork W2418099440 @default.
• W2889372758 hasRelatedWork W2464262298 @default.
• W2889372758 hasRelatedWork W2570648142 @default.
• W2889372758 hasRelatedWork W3101164993 @default.
• W2889372758 hasVolume "51" @default.
• W2889372758 isParatext "false" @default.
• W2889372758 isRetracted "false" @default.
• W2889372758 magId "2889372758" @default.

• next