FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889473803> ?p ?o ?g. }

• W2889473803 endingPage "176" @default.
• W2889473803 startingPage "171" @default.
• W2889473803 abstract "An increasing number of studies have elucidated the essential roles of long noncoding RNAs (lncRNAs) in tumor development. LncRNAs are also closely associated with bladder cancer (BCa) progression. In the present study, we screened out a novel lncRNA CALML3-AS1 with increased expression value in BCa tissues. Particularly, we showed that CALML3-AS1 overexpression correlates with advanced staging and an unsatisfactory prognosis. Functional experiments illustrated that CALML3-AS1 knockdown suppressed BCa cell proliferation, arrested cell-cycle progression and impaired migration and invasion while promoting apoptosis. Mechanistic investigation revealed that CALML3-AS1 directly interacts with miR-4316 and inhibits its availability in BCa cells, leading to elevated expression of ZBTB2. Consequently, ZBTB2 promotes BCa tumorigenesis through repressing p21 and facilitating PDK4 transcription. In conclusion, our findings demonstrate a novel CALML3-AS1-mediated process involved in BCa progression and indicate it might be a promising therapeutic target." @default.
• W2889473803 created "2018-09-07" @default.
• W2889473803 creator A5006077725 @default.
• W2889473803 creator A5006469758 @default.
• W2889473803 creator A5007767899 @default.
• W2889473803 creator A5013786814 @default.
• W2889473803 creator A5031164641 @default.
• W2889473803 creator A5052148680 @default.
• W2889473803 date "2018-09-01" @default.
• W2889473803 modified "2023-09-26" @default.
• W2889473803 title "LncRNA CALML3-AS1 promotes tumorigenesis of bladder cancer via regulating ZBTB2 by suppression of microRNA-4316" @default.
• W2889473803 cites W2034373123 @default.
• W2889473803 cites W2040061884 @default.
• W2889473803 cites W2065430663 @default.
• W2889473803 cites W2139351795 @default.
• W2889473803 cites W2162547088 @default.
• W2889473803 cites W2235523093 @default.
• W2889473803 cites W2419277740 @default.
• W2889473803 cites W2558639270 @default.
• W2889473803 cites W2588715080 @default.
• W2889473803 cites W2603752903 @default.
• W2889473803 cites W2769902165 @default.
• W2889473803 cites W2785637603 @default.
• W2889473803 cites W2787150042 @default.
• W2889473803 cites W2796484569 @default.
• W2889473803 cites W2799274690 @default.
• W2889473803 cites W2801335122 @default.
• W2889473803 cites W2804126702 @default.
• W2889473803 cites W2804154867 @default.
• W2889473803 cites W2804292789 @default.
• W2889473803 cites W2805029132 @default.
• W2889473803 cites W2805480449 @default.
• W2889473803 cites W2808061953 @default.
• W2889473803 cites W2868193188 @default.
• W2889473803 cites W2883693740 @default.
• W2889473803 doi "https://doi.org/10.1016/j.bbrc.2018.08.150" @default.
• W2889473803 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30177388" @default.
• W2889473803 hasPublicationYear "2018" @default.
• W2889473803 type Work @default.
• W2889473803 sameAs 2889473803 @default.
• W2889473803 citedByCount "30" @default.
• W2889473803 countsByYear W28894738032018 @default.
• W2889473803 countsByYear W28894738032019 @default.
• W2889473803 countsByYear W28894738032020 @default.
• W2889473803 countsByYear W28894738032021 @default.
• W2889473803 countsByYear W28894738032022 @default.
• W2889473803 countsByYear W28894738032023 @default.
• W2889473803 crossrefType "journal-article" @default.
• W2889473803 hasAuthorship W2889473803A5006077725 @default.
• W2889473803 hasAuthorship W2889473803A5006469758 @default.
• W2889473803 hasAuthorship W2889473803A5007767899 @default.
• W2889473803 hasAuthorship W2889473803A5013786814 @default.
• W2889473803 hasAuthorship W2889473803A5031164641 @default.
• W2889473803 hasAuthorship W2889473803A5052148680 @default.
• W2889473803 hasConcept C104317684 @default.
• W2889473803 hasConcept C121608353 @default.
• W2889473803 hasConcept C127561419 @default.
• W2889473803 hasConcept C138885662 @default.
• W2889473803 hasConcept C145059251 @default.
• W2889473803 hasConcept C153911025 @default.
• W2889473803 hasConcept C173396325 @default.
• W2889473803 hasConcept C179926584 @default.
• W2889473803 hasConcept C190283241 @default.
• W2889473803 hasConcept C2779256057 @default.
• W2889473803 hasConcept C2780352672 @default.
• W2889473803 hasConcept C2781018059 @default.
• W2889473803 hasConcept C29537977 @default.
• W2889473803 hasConcept C41895202 @default.
• W2889473803 hasConcept C502942594 @default.
• W2889473803 hasConcept C54355233 @default.
• W2889473803 hasConcept C555283112 @default.
• W2889473803 hasConcept C62112901 @default.
• W2889473803 hasConcept C62203573 @default.
• W2889473803 hasConcept C86339819 @default.
• W2889473803 hasConcept C86803240 @default.
• W2889473803 hasConceptScore W2889473803C104317684 @default.
• W2889473803 hasConceptScore W2889473803C121608353 @default.
• W2889473803 hasConceptScore W2889473803C127561419 @default.
• W2889473803 hasConceptScore W2889473803C138885662 @default.
• W2889473803 hasConceptScore W2889473803C145059251 @default.
• W2889473803 hasConceptScore W2889473803C153911025 @default.
• W2889473803 hasConceptScore W2889473803C173396325 @default.
• W2889473803 hasConceptScore W2889473803C179926584 @default.
• W2889473803 hasConceptScore W2889473803C190283241 @default.
• W2889473803 hasConceptScore W2889473803C2779256057 @default.
• W2889473803 hasConceptScore W2889473803C2780352672 @default.
• W2889473803 hasConceptScore W2889473803C2781018059 @default.
• W2889473803 hasConceptScore W2889473803C29537977 @default.
• W2889473803 hasConceptScore W2889473803C41895202 @default.
• W2889473803 hasConceptScore W2889473803C502942594 @default.
• W2889473803 hasConceptScore W2889473803C54355233 @default.
• W2889473803 hasConceptScore W2889473803C555283112 @default.
• W2889473803 hasConceptScore W2889473803C62112901 @default.
• W2889473803 hasConceptScore W2889473803C62203573 @default.
• W2889473803 hasConceptScore W2889473803C86339819 @default.
• W2889473803 hasConceptScore W2889473803C86803240 @default.
• W2889473803 hasFunder F4320338464 @default.
• W2889473803 hasIssue "1" @default.

• next