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- W2889723211 abstract "There is contradictory evidence in the literature with respect to diagnosis and management of follicular lesions of the thyroid gland. From a surgical pathology standpoint, pathologists require submission and processing of the entire capsule for microscopic evaluation. This can be extremely challenging, especially in larger lesions. We studied the impact of submitting an entire capsule on final pathologic diagnosis in cases on which only representative sections were submitted initially and the entire capsule was submitted subsequently. A total of 80 specimens were identified. Mean initial sections submitted were 11.6 ± 3.6. Entire capsule was submitted subsequently in 12.6 ± 13.3 sections. Submission of the entire capsule contributed to a final diagnosis in three (3.8%) cases. There was no significant difference in the requirement of subsequent sections in specimens grossed by residents compared to those grossed by pathologist assistants (10.4 ± 10.8 vs 14.4 ± 14.9, P = .18). Cases signed out by cytopathologists required less subsequent sections compared to those signed out by hematopathologists or general surgical pathologists, but the P value was statistically insignificant (P = .81). Subsequent processing cost $4,132.8 in these cases. Processing of the entire capsule in thyroid follicular lesions has a definitive yield that comes at a high cost. Thin slicing and looking for areas of gross abnormality such as mushrooming may be more practical, especially in larger lesions." @default.
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- W2889723211 date "2018-09-21" @default.
- W2889723211 modified "2023-09-27" @default.
- W2889723211 title "Effectiveness of Processing the Entire Capsule in Cases of Thyroid Follicular Lesions" @default.
- W2889723211 doi "https://doi.org/10.1093/ajcp/aqy090.047" @default.
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