FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889762585> ?p ?o ?g. }

• W2889762585 endingPage "193" @default.
• W2889762585 startingPage "187" @default.
• W2889762585 abstract "ADP-ribosylation factor-like3 (ARL3) is a member of the ADP-ribosylation factor family of GTP-binding proteins that plays important role in regulating Ciliary trafficking. It ubiquitously expressed in normal tissues and tumor cell lines. However, the location and function of ARL3 in organelles are rarely known. In this study, we explored ARL3 subcellular localization in an all-round way in HEK293T, Neuro-2A and U251 cells by density gradient centrifugation and immunofluorescence. The results showed that ARL3 is expressed in most of organelles, and an iodixonal step gradient was further confirmed that ARL3 is mainly localized to the mitochondria, endosomes, lysosomes, and proteasome. By molecular functional analysis, we observed that ARL3 promotes the aggregation of GFP-LC3, up-regulation of LC3-II/LC3-I and down-regulation of SQSMT1/BECN1, and knocking down of ARL3 inbibits autophagy, which suggested that ARL3 is necessary for autophagy. this study presents a comprehensive evaluation of the subcellular localization for ARL3 and provides important on understanding the functions of ARL3." @default.
• W2889762585 created "2018-09-27" @default.
• W2889762585 creator A5016770711 @default.
• W2889762585 creator A5030147577 @default.
• W2889762585 creator A5030187457 @default.
• W2889762585 creator A5035671169 @default.
• W2889762585 creator A5080488850 @default.
• W2889762585 date "2018-11-01" @default.
• W2889762585 modified "2023-10-15" @default.
• W2889762585 title "ARL3 subcellular localization and its suspected role in autophagy" @default.
• W2889762585 cites W1565206912 @default.
• W2889762585 cites W1964856412 @default.
• W2889762585 cites W1965680695 @default.
• W2889762585 cites W1978974783 @default.
• W2889762585 cites W1988226150 @default.
• W2889762585 cites W2062951860 @default.
• W2889762585 cites W2068801471 @default.
• W2889762585 cites W2071406790 @default.
• W2889762585 cites W2077351975 @default.
• W2889762585 cites W2084234962 @default.
• W2889762585 cites W2099008080 @default.
• W2889762585 cites W2120001077 @default.
• W2889762585 cites W2126210676 @default.
• W2889762585 cites W2137621971 @default.
• W2889762585 cites W2149117501 @default.
• W2889762585 cites W22307913 @default.
• W2889762585 cites W2284652860 @default.
• W2889762585 cites W2316888719 @default.
• W2889762585 cites W2536364763 @default.
• W2889762585 cites W2548499955 @default.
• W2889762585 cites W2606924433 @default.
• W2889762585 cites W2766320206 @default.
• W2889762585 doi "https://doi.org/10.1016/j.biochi.2018.09.007" @default.
• W2889762585 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30227171" @default.
• W2889762585 hasPublicationYear "2018" @default.
• W2889762585 type Work @default.
• W2889762585 sameAs 2889762585 @default.
• W2889762585 citedByCount "6" @default.
• W2889762585 countsByYear W28897625852019 @default.
• W2889762585 countsByYear W28897625852020 @default.
• W2889762585 countsByYear W28897625852021 @default.
• W2889762585 countsByYear W28897625852022 @default.
• W2889762585 countsByYear W28897625852023 @default.
• W2889762585 crossrefType "journal-article" @default.
• W2889762585 hasAuthorship W2889762585A5016770711 @default.
• W2889762585 hasAuthorship W2889762585A5030147577 @default.
• W2889762585 hasAuthorship W2889762585A5030187457 @default.
• W2889762585 hasAuthorship W2889762585A5035671169 @default.
• W2889762585 hasAuthorship W2889762585A5080488850 @default.
• W2889762585 hasConcept C102747710 @default.
• W2889762585 hasConcept C119062480 @default.
• W2889762585 hasConcept C124682485 @default.
• W2889762585 hasConcept C132946820 @default.
• W2889762585 hasConcept C153911025 @default.
• W2889762585 hasConcept C158617107 @default.
• W2889762585 hasConcept C168240541 @default.
• W2889762585 hasConcept C181199279 @default.
• W2889762585 hasConcept C190062978 @default.
• W2889762585 hasConcept C190283241 @default.
• W2889762585 hasConcept C203522944 @default.
• W2889762585 hasConcept C27740335 @default.
• W2889762585 hasConcept C2776879804 @default.
• W2889762585 hasConcept C2777122948 @default.
• W2889762585 hasConcept C2780216420 @default.
• W2889762585 hasConcept C28859421 @default.
• W2889762585 hasConcept C55493867 @default.
• W2889762585 hasConcept C79879829 @default.
• W2889762585 hasConcept C86803240 @default.
• W2889762585 hasConcept C95444343 @default.
• W2889762585 hasConceptScore W2889762585C102747710 @default.
• W2889762585 hasConceptScore W2889762585C119062480 @default.
• W2889762585 hasConceptScore W2889762585C124682485 @default.
• W2889762585 hasConceptScore W2889762585C132946820 @default.
• W2889762585 hasConceptScore W2889762585C153911025 @default.
• W2889762585 hasConceptScore W2889762585C158617107 @default.
• W2889762585 hasConceptScore W2889762585C168240541 @default.
• W2889762585 hasConceptScore W2889762585C181199279 @default.
• W2889762585 hasConceptScore W2889762585C190062978 @default.
• W2889762585 hasConceptScore W2889762585C190283241 @default.
• W2889762585 hasConceptScore W2889762585C203522944 @default.
• W2889762585 hasConceptScore W2889762585C27740335 @default.
• W2889762585 hasConceptScore W2889762585C2776879804 @default.
• W2889762585 hasConceptScore W2889762585C2777122948 @default.
• W2889762585 hasConceptScore W2889762585C2780216420 @default.
• W2889762585 hasConceptScore W2889762585C28859421 @default.
• W2889762585 hasConceptScore W2889762585C55493867 @default.
• W2889762585 hasConceptScore W2889762585C79879829 @default.
• W2889762585 hasConceptScore W2889762585C86803240 @default.
• W2889762585 hasConceptScore W2889762585C95444343 @default.
• W2889762585 hasFunder F4320321001 @default.
• W2889762585 hasFunder F4320321881 @default.
• W2889762585 hasLocation W28897625851 @default.
• W2889762585 hasLocation W28897625852 @default.
• W2889762585 hasOpenAccess W2889762585 @default.
• W2889762585 hasPrimaryLocation W28897625851 @default.
• W2889762585 hasRelatedWork W1584776143 @default.
• W2889762585 hasRelatedWork W1992425154 @default.
• W2889762585 hasRelatedWork W2026830389 @default.

• next