Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889768695> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2889768695 endingPage "950" @default.
- W2889768695 startingPage "944" @default.
- W2889768695 abstract "An unresponsive patient's need and their response to breakthrough medication is determined by clinical assessment and/or observational measures. How closely these methods match the patient's experience is unknown.Determine the efficacy and effectiveness of breakthrough medication in unresponsive patients and the perception of patient comfort made by nurses and family.A prospective study of breakthrough medication in unresponsive patients. The Richmond Agitation-Sedation Scale (RASS) and Patient Comfort Score (PCS) were compared with time-matched Bispectral Index (BIS) Scores. The effects of opioid vs. opioid + benzodiazepine breakthroughs and the relation between synchronous nurse and family measurements of the PCS were evaluated. Analysis of variance and paired t-tests were used for BIS analyses and nonparametric Mann-Whitney tests for RASS and PCS.Significant reductions at 30 and 60 minutes after breakthrough medication were noted for BIS (P < 0.0004), RASS (P = 0.043 and 0.004, respectively), and PCS (P < 0.0004). A direct comparison of the effect of opioid breakthrough medication vs. opioid plus benzodiazepine revealed no significant difference (BIS, P = 0.512; RASS, P = 0.195; PCS, P = 0.119). Of the 157 synchronous nurse and family measures of patient comfort, families rated patient discomfort significantly higher than nurses (P < 0.0004).This study provides additional evidence for the efficacy and effectiveness of breakthrough medication and the merit of observational measures in determining a patient's response. The onset of action is evident at 30 minutes after injection. Family assessment of patient comfort may be more nuanced than that of nurses, and they not uncommonly rate patient discomfort higher than nurses." @default.
- W2889768695 created "2018-09-27" @default.
- W2889768695 creator A5017595008 @default.
- W2889768695 creator A5042485421 @default.
- W2889768695 creator A5065006281 @default.
- W2889768695 creator A5068116723 @default.
- W2889768695 date "2018-12-01" @default.
- W2889768695 modified "2023-09-26" @default.
- W2889768695 title "Breakthrough Medication in Unresponsive Palliative Care Patients: Indications, Practice, and Efficacy" @default.
- W2889768695 cites W1985853998 @default.
- W2889768695 cites W2000613096 @default.
- W2889768695 cites W2002211280 @default.
- W2889768695 cites W2039279414 @default.
- W2889768695 cites W2050637946 @default.
- W2889768695 cites W2073051214 @default.
- W2889768695 cites W2078296269 @default.
- W2889768695 cites W2095250018 @default.
- W2889768695 cites W2110729317 @default.
- W2889768695 cites W2117350172 @default.
- W2889768695 cites W2120711353 @default.
- W2889768695 cites W2123098876 @default.
- W2889768695 cites W2124868672 @default.
- W2889768695 cites W2148573658 @default.
- W2889768695 cites W2156337763 @default.
- W2889768695 cites W2156567596 @default.
- W2889768695 cites W2405860614 @default.
- W2889768695 cites W2406776487 @default.
- W2889768695 cites W2420065473 @default.
- W2889768695 cites W2519259834 @default.
- W2889768695 cites W2568681340 @default.
- W2889768695 cites W2571444756 @default.
- W2889768695 cites W2609129448 @default.
- W2889768695 cites W2744645956 @default.
- W2889768695 cites W2749081185 @default.
- W2889768695 cites W4237872303 @default.
- W2889768695 doi "https://doi.org/10.1016/j.jpainsymman.2018.08.020" @default.
- W2889768695 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30201486" @default.
- W2889768695 hasPublicationYear "2018" @default.
- W2889768695 type Work @default.
- W2889768695 sameAs 2889768695 @default.
- W2889768695 citedByCount "3" @default.
- W2889768695 countsByYear W28897686952019 @default.
- W2889768695 countsByYear W28897686952021 @default.
- W2889768695 crossrefType "journal-article" @default.
- W2889768695 hasAuthorship W2889768695A5017595008 @default.
- W2889768695 hasAuthorship W2889768695A5042485421 @default.
- W2889768695 hasAuthorship W2889768695A5065006281 @default.
- W2889768695 hasAuthorship W2889768695A5068116723 @default.
- W2889768695 hasBestOaLocation W28897686951 @default.
- W2889768695 hasConcept C126322002 @default.
- W2889768695 hasConcept C170493617 @default.
- W2889768695 hasConcept C1862650 @default.
- W2889768695 hasConcept C23131810 @default.
- W2889768695 hasConcept C2776814716 @default.
- W2889768695 hasConcept C2778173252 @default.
- W2889768695 hasConcept C2781063702 @default.
- W2889768695 hasConcept C42219234 @default.
- W2889768695 hasConcept C71924100 @default.
- W2889768695 hasConceptScore W2889768695C126322002 @default.
- W2889768695 hasConceptScore W2889768695C170493617 @default.
- W2889768695 hasConceptScore W2889768695C1862650 @default.
- W2889768695 hasConceptScore W2889768695C23131810 @default.
- W2889768695 hasConceptScore W2889768695C2776814716 @default.
- W2889768695 hasConceptScore W2889768695C2778173252 @default.
- W2889768695 hasConceptScore W2889768695C2781063702 @default.
- W2889768695 hasConceptScore W2889768695C42219234 @default.
- W2889768695 hasConceptScore W2889768695C71924100 @default.
- W2889768695 hasIssue "6" @default.
- W2889768695 hasLocation W28897686951 @default.
- W2889768695 hasLocation W28897686952 @default.
- W2889768695 hasOpenAccess W2889768695 @default.
- W2889768695 hasPrimaryLocation W28897686951 @default.
- W2889768695 hasRelatedWork W1969676254 @default.
- W2889768695 hasRelatedWork W1989395640 @default.
- W2889768695 hasRelatedWork W2038101840 @default.
- W2889768695 hasRelatedWork W2124345810 @default.
- W2889768695 hasRelatedWork W2405810433 @default.
- W2889768695 hasRelatedWork W2405817727 @default.
- W2889768695 hasRelatedWork W2411727155 @default.
- W2889768695 hasRelatedWork W2443936009 @default.
- W2889768695 hasRelatedWork W3185240436 @default.
- W2889768695 hasRelatedWork W4299966385 @default.
- W2889768695 hasVolume "56" @default.
- W2889768695 isParatext "false" @default.
- W2889768695 isRetracted "false" @default.
- W2889768695 magId "2889768695" @default.
- W2889768695 workType "article" @default.