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- W2889774807 abstract "Libraries of antibody fragments displayed on filamentous phages are now a widely used approach to isolate antibodies against virtually any target. We describe a simple protocol to make large and diverse libraries based on a single or a limited number of frameworks. The approach is flexible enough to be used with any antibody format, either single-chain (scFv, VHH) or multi-chain (Fv, Fab, (Fab')2), and to target in a single step the six complementarity-determining regions-or any other part-of the antibody molecule. Using this protocol, libraries larger than 1010 can be constructed in a single week." @default.
- W2889774807 created "2018-09-27" @default.
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- W2889774807 date "2018-01-01" @default.
- W2889774807 modified "2023-09-25" @default.
- W2889774807 title "Construction of Synthetic Antibody Libraries" @default.
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- W2889774807 doi "https://doi.org/10.1007/978-1-4939-8648-4_5" @default.
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- W2889774807 hasPublicationYear "2018" @default.
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