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- W2889777963 abstract "A photoredox-mediated direct cross-dehydrogenative coupling reaction to accomplish α-aminoalkylation of N-heteroarenes is reported. This mild reaction has a broad substrate scope, offers the first general method for synthesis of aminoalkylated N-heteroarenes without the need for substrate prefunctionalization, and is scalable to the gram level. Furthermore, the reaction was found to be applicable to other hydrogen donors besides amines (i.e., ethers, an aldehyde, a formamide, p-xylene, and alkanes), thus enabling the preparation of N-heteroarenes bearing various types of substituents." @default.
- W2889777963 created "2018-09-27" @default.
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- W2889777963 date "2018-09-04" @default.
- W2889777963 modified "2023-10-14" @default.
- W2889777963 title "Photoredox-Mediated Direct Cross-Dehydrogenative Coupling of Heteroarenes and Amines" @default.
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- W2889777963 doi "https://doi.org/10.1021/acs.orglett.8b02389" @default.
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