FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889824172> ?p ?o ?g. }

• W2889824172 endingPage "59" @default.
• W2889824172 startingPage "52" @default.
• W2889824172 abstract "This work demonstrates the feasibility of the extemporaneous preparation of maltodextrins orodispersible films (ODF) by hot-melt ram-extrusion 3D printing. This method consists of three simple technological operations which can be also implemented in a pharmacy setting. First, maltodextrins, drug, and other excipients are mixed in a mortar and wetted with the plasticizer (i.e. glycerine). Then, the mixture is fed in the chamber of the ram-extruder and heated. ODF are individually printed on the packaging material foil and sealed without further manipulations. The critical formulation attributes and process variables were investigated to define the processability space. In particular, the optimal conditions to print a mixture of maltodextrins/glycerine in a 80/20 w/w ratio resulted: heating temperature: 85 °C; needle gauge: 18 G; needle-packaging material foil distance: 0.6 mm; maximum print rate: 50 mm/s; filling angle: 120°. The maximum drug loading was about 40%, when paracetamol was used as model drug. The compounded ODF complied with USP and Ph. Eur. specifications for disintegration time (<1 min). The dissolution pattern of paracetamol overlapped with that obtained from ODF with a similar composition prepared by the consolidated solvent casting technique, demonstrating the suitability of the proposed technology." @default.
• W2889824172 created "2018-09-27" @default.
• W2889824172 creator A5008550722 @default.
• W2889824172 creator A5025720794 @default.
• W2889824172 creator A5030117086 @default.
• W2889824172 creator A5051686453 @default.
• W2889824172 creator A5059225761 @default.
• W2889824172 creator A5087483239 @default.
• W2889824172 date "2018-11-01" @default.
• W2889824172 modified "2023-10-17" @default.
• W2889824172 title "Personalized orodispersible films by hot melt ram extrusion 3D printing" @default.
• W2889824172 cites W1800265830 @default.
• W2889824172 cites W2005731876 @default.
• W2889824172 cites W2011873158 @default.
• W2889824172 cites W2013926500 @default.
• W2889824172 cites W2025040104 @default.
• W2889824172 cites W2044572427 @default.
• W2889824172 cites W2050713872 @default.
• W2889824172 cites W2053950260 @default.
• W2889824172 cites W2061110091 @default.
• W2889824172 cites W2089583142 @default.
• W2889824172 cites W2093649719 @default.
• W2889824172 cites W2120241930 @default.
• W2889824172 cites W2340805991 @default.
• W2889824172 cites W2475561070 @default.
• W2889824172 cites W2596547636 @default.
• W2889824172 cites W2611766114 @default.
• W2889824172 cites W2617550216 @default.
• W2889824172 cites W2622002125 @default.
• W2889824172 cites W2752598143 @default.
• W2889824172 cites W2763739906 @default.
• W2889824172 cites W2765914793 @default.
• W2889824172 cites W2770931345 @default.
• W2889824172 cites W2783197708 @default.
• W2889824172 cites W2793737494 @default.
• W2889824172 cites W2795363903 @default.
• W2889824172 cites W2802838852 @default.
• W2889824172 cites W2804356987 @default.
• W2889824172 cites W2804715583 @default.
• W2889824172 cites W2886939254 @default.
• W2889824172 cites W4256684293 @default.
• W2889824172 doi "https://doi.org/10.1016/j.ijpharm.2018.09.013" @default.
• W2889824172 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30205128" @default.
• W2889824172 hasPublicationYear "2018" @default.
• W2889824172 type Work @default.
• W2889824172 sameAs 2889824172 @default.
• W2889824172 citedByCount "74" @default.
• W2889824172 countsByYear W28898241722019 @default.
• W2889824172 countsByYear W28898241722020 @default.
• W2889824172 countsByYear W28898241722021 @default.
• W2889824172 countsByYear W28898241722022 @default.
• W2889824172 countsByYear W28898241722023 @default.
• W2889824172 crossrefType "journal-article" @default.
• W2889824172 hasAuthorship W2889824172A5008550722 @default.
• W2889824172 hasAuthorship W2889824172A5025720794 @default.
• W2889824172 hasAuthorship W2889824172A5030117086 @default.
• W2889824172 hasAuthorship W2889824172A5051686453 @default.
• W2889824172 hasAuthorship W2889824172A5059225761 @default.
• W2889824172 hasAuthorship W2889824172A5087483239 @default.
• W2889824172 hasBestOaLocation W28898241722 @default.
• W2889824172 hasConcept C127413603 @default.
• W2889824172 hasConcept C136229726 @default.
• W2889824172 hasConcept C159985019 @default.
• W2889824172 hasConcept C185592680 @default.
• W2889824172 hasConcept C192562407 @default.
• W2889824172 hasConcept C2778958987 @default.
• W2889824172 hasConcept C3019308078 @default.
• W2889824172 hasConcept C42360764 @default.
• W2889824172 hasConcept C43617362 @default.
• W2889824172 hasConcept C58968531 @default.
• W2889824172 hasConcept C71924100 @default.
• W2889824172 hasConcept C7363328 @default.
• W2889824172 hasConcept C77281830 @default.
• W2889824172 hasConcept C88380143 @default.
• W2889824172 hasConcept C97103648 @default.
• W2889824172 hasConceptScore W2889824172C127413603 @default.
• W2889824172 hasConceptScore W2889824172C136229726 @default.
• W2889824172 hasConceptScore W2889824172C159985019 @default.
• W2889824172 hasConceptScore W2889824172C185592680 @default.
• W2889824172 hasConceptScore W2889824172C192562407 @default.
• W2889824172 hasConceptScore W2889824172C2778958987 @default.
• W2889824172 hasConceptScore W2889824172C3019308078 @default.
• W2889824172 hasConceptScore W2889824172C42360764 @default.
• W2889824172 hasConceptScore W2889824172C43617362 @default.
• W2889824172 hasConceptScore W2889824172C58968531 @default.
• W2889824172 hasConceptScore W2889824172C71924100 @default.
• W2889824172 hasConceptScore W2889824172C7363328 @default.
• W2889824172 hasConceptScore W2889824172C77281830 @default.
• W2889824172 hasConceptScore W2889824172C88380143 @default.
• W2889824172 hasConceptScore W2889824172C97103648 @default.
• W2889824172 hasIssue "1-2" @default.
• W2889824172 hasLocation W28898241721 @default.
• W2889824172 hasLocation W28898241722 @default.
• W2889824172 hasLocation W28898241723 @default.
• W2889824172 hasOpenAccess W2889824172 @default.
• W2889824172 hasPrimaryLocation W28898241721 @default.
• W2889824172 hasRelatedWork W1964050266 @default.
• W2889824172 hasRelatedWork W2042665261 @default.

• next