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- W2889849008 abstract "<h3>Importance</h3> Critical to the success of many medical therapeutics is a consideration of the brain’s miraculous ability to dynamically rewire itself anatomically and neurochemically on the basis of incoming information. We argue that white noise exposure, a commonly recommended therapy for patients with tinnitus, engages these plastic processes in a way that induces maladaptive changes in the brain that degrade neurological health and compromise cognition. <h3>Observations</h3> The pathophysiologic mechanisms commonly associated with hearing loss and tinnitus reflect cortical dedifferentiation and widespread loss of inhibitory tone throughout the central auditory pathway. Importantly, these same changes are also induced by exposure to unstructured noise, even at nontraumatic levels in the adult nervous system. Not by coincidence, the same changes appear in age-related decline of central auditory function, suggesting that both tinnitus and white noise accelerate the aging of the brain. <h3>Conclusions and Relevance</h3> Noise exposure therapies offer a seductive short-term solution for relief but, in the long term, undermine the functional and structural integrity of the central auditory system and the brain more generally. Sound therapies using unstructured, random (“white”) noise should be avoided as a treatment for tinnitus. Alternative therapeutics that drive positive, adaptive plastic changes are discussed." @default.
- W2889849008 created "2018-09-27" @default.
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- W2889849008 date "2018-10-01" @default.
- W2889849008 modified "2023-10-14" @default.
- W2889849008 title "Unintended Consequences of White Noise Therapy for Tinnitus—Otolaryngology's Cobra Effect" @default.
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- W2889849008 doi "https://doi.org/10.1001/jamaoto.2018.1856" @default.
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