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• W2889894889 endingPage "298" @default.
• W2889894889 startingPage "290" @default.
• W2889894889 abstract "The acute respiratory distress syndrome (ARDS) is a serious and common complication of multiple medical and surgical interventions, with sepsis, pneumonia, and aspiration of gastric contents being common risk factors. ARDS develops within 1 week of a known clinical insult or presents with new/worsening respiratory symptoms if the clinical insult is unknown. Approximately 40% of the ARDS cases have a fatal outcome. Transfusion-related acute lung injury (TRALI), on the other hand, is characterized by the occurrence of respiratory distress and acute lung injury, which presents within 6 h after administration of a blood transfusion. In contrast to ARDS, acute lung injury in TRALI is not attributable to another risk factor for acute lung injury. ‘Possible TRALI', however, may have a clear temporal relationship to an alternative risk factor for acute lung injury. Risk factors for TRALI include chronic alcohol abuse and systemic inflammation. TRALI is the leading cause of transfusion-related fatalities. There are no specific therapies available for ARDS or TRALI as both have a complex and incompletely understood pathogenesis. Neutrophils (polymorphonuclear leukocytes; PMNs) have been suggested to be key effector cells in the pathogenesis of both syndromes. In the present paper, we summarize the literature with regard to PMN involvement in the pathogenesis of both ARDS and TRALI based on both human data as well as on animal models. The evidence generally supports a strong role for PMNs in both ARDS and TRALI. More research is required to shed light on the pathogenesis of these respiratory syndromes and to more thoroughly establish the nature of the PMN involvement, especially considering the heterogeneous etiologies of ARDS." @default.
• W2889894889 created "2018-09-27" @default.
• W2889894889 creator A5028539767 @default.
• W2889894889 creator A5029112896 @default.
• W2889894889 creator A5088829948 @default.
• W2889894889 date "2018-01-01" @default.
• W2889894889 modified "2023-10-11" @default.
• W2889894889 title "The Pathogenic Involvement of Neutrophils in Acute Respiratory Distress Syndrome and Transfusion-Related Acute Lung Injury" @default.
• W2889894889 cites W1581533309 @default.
• W2889894889 cites W1591434355 @default.
• W2889894889 cites W1600560134 @default.
• W2889894889 cites W1705619492 @default.
• W2889894889 cites W1803784511 @default.
• W2889894889 cites W1851211013 @default.
• W2889894889 cites W1877315027 @default.
• W2889894889 cites W1913879859 @default.
• W2889894889 cites W1915340945 @default.
• W2889894889 cites W1918928165 @default.
• W2889894889 cites W1920044084 @default.
• W2889894889 cites W1926513165 @default.
• W2889894889 cites W1956073601 @default.
• W2889894889 cites W1964906546 @default.
• W2889894889 cites W1965614926 @default.
• W2889894889 cites W1967640548 @default.
• W2889894889 cites W1970147808 @default.
• W2889894889 cites W1970221391 @default.
• W2889894889 cites W1971090322 @default.
• W2889894889 cites W1971246306 @default.
• W2889894889 cites W1973163555 @default.
• W2889894889 cites W1976656820 @default.
• W2889894889 cites W1976922810 @default.
• W2889894889 cites W1981878182 @default.
• W2889894889 cites W1982808406 @default.
• W2889894889 cites W1983297645 @default.
• W2889894889 cites W1983318857 @default.
• W2889894889 cites W1983331181 @default.
• W2889894889 cites W1984549408 @default.
• W2889894889 cites W1986063899 @default.
• W2889894889 cites W1992729512 @default.
• W2889894889 cites W1994326369 @default.
• W2889894889 cites W1994813233 @default.
• W2889894889 cites W1994965038 @default.
• W2889894889 cites W1997731894 @default.
• W2889894889 cites W1998463177 @default.
• W2889894889 cites W2000566901 @default.
• W2889894889 cites W2003199416 @default.
• W2889894889 cites W2004668542 @default.
• W2889894889 cites W2007125759 @default.
• W2889894889 cites W2010284674 @default.
• W2889894889 cites W2012346751 @default.
• W2889894889 cites W2019002691 @default.
• W2889894889 cites W2022353505 @default.
• W2889894889 cites W2023404773 @default.
• W2889894889 cites W2027370397 @default.
• W2889894889 cites W2027935910 @default.
• W2889894889 cites W2032227357 @default.
• W2889894889 cites W2034224484 @default.
• W2889894889 cites W2036035391 @default.
• W2889894889 cites W2037459166 @default.
• W2889894889 cites W2041806010 @default.
• W2889894889 cites W2041944580 @default.
• W2889894889 cites W2046411273 @default.
• W2889894889 cites W2047406342 @default.
• W2889894889 cites W2048083566 @default.
• W2889894889 cites W2055376647 @default.
• W2889894889 cites W2056121897 @default.
• W2889894889 cites W2060790984 @default.
• W2889894889 cites W2064029287 @default.
• W2889894889 cites W2064220369 @default.
• W2889894889 cites W2067922517 @default.
• W2889894889 cites W2069832329 @default.
• W2889894889 cites W2076811044 @default.
• W2889894889 cites W2080771516 @default.
• W2889894889 cites W2082757358 @default.
• W2889894889 cites W2085417919 @default.
• W2889894889 cites W2089782191 @default.
• W2889894889 cites W2090755276 @default.
• W2889894889 cites W2092514430 @default.
• W2889894889 cites W2092616294 @default.
• W2889894889 cites W2092879755 @default.
• W2889894889 cites W2101780675 @default.
• W2889894889 cites W2104351898 @default.
• W2889894889 cites W2104779801 @default.
• W2889894889 cites W2104934425 @default.
• W2889894889 cites W2111742038 @default.
• W2889894889 cites W2111939342 @default.
• W2889894889 cites W2117774868 @default.
• W2889894889 cites W2119811828 @default.
• W2889894889 cites W2120430262 @default.
• W2889894889 cites W2123128671 @default.
• W2889894889 cites W2124809804 @default.
• W2889894889 cites W2129215592 @default.
• W2889894889 cites W2129339954 @default.
• W2889894889 cites W2129897825 @default.
• W2889894889 cites W2142023493 @default.
• W2889894889 cites W2143152020 @default.
• W2889894889 cites W2144203350 @default.
• W2889894889 cites W2153178129 @default.

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