FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2889917226> ?p ?o ?g. }

• W2889917226 endingPage "563" @default.
• W2889917226 startingPage "555" @default.
• W2889917226 abstract "With the rapidly growing number of macromolecular structures solved to near-atomic resolution using electron cryomicroscopy (cryoEM), map interpretation and model building directly from the density without the use of structural templates has become increasingly important. As part of the 2015/2016 Map and Model Challenge, we attempted to assess our latest de novo modeling tool, Pathwalking, in terms of performance and usability, as well as identify areas for future improvements. In total, we applied Pathwalking to six density maps between 3 and 4.5 Å resolution selected from the challenge data sets. In five of the six cases, Pathwalking was able to accurately determine the protein fold and in three of these cases, the final all atom model had less than 1.6 Å RMSD when compared to the known structure. Model building and refinement was nearly completely automated, used default parameters and took less than 30 min to complete a refined all atom model. A direct outgrowth of this work was a more streamlined automated command line Pathwalking utility, as well as a novel sequence assignment and optimization routine, which attempts to register sidechain density with expected side chain volume. In total, Pathwalking offers a nearly complete, robust and efficient method for constructing atomistic protein structures directly from a density map without the aid of a template." @default.
• W2889917226 created "2018-09-27" @default.
• W2889917226 creator A5055564291 @default.
• W2889917226 creator A5071083916 @default.
• W2889917226 date "2018-12-01" @default.
• W2889917226 modified "2023-10-16" @default.
• W2889917226 title "Automation and assessment of de novo modeling with Pathwalking in near atomic resolution cryoEM density maps" @default.
• W2889917226 cites W1546727782 @default.
• W2889917226 cites W1810581179 @default.
• W2889917226 cites W1980885982 @default.
• W2889917226 cites W1985145180 @default.
• W2889917226 cites W2009061886 @default.
• W2889917226 cites W2010158007 @default.
• W2889917226 cites W2013315897 @default.
• W2889917226 cites W2017708378 @default.
• W2889917226 cites W2030109606 @default.
• W2889917226 cites W2040940915 @default.
• W2889917226 cites W2064140868 @default.
• W2889917226 cites W2067374400 @default.
• W2889917226 cites W2095748904 @default.
• W2889917226 cites W2104130324 @default.
• W2889917226 cites W2114850508 @default.
• W2889917226 cites W2120396539 @default.
• W2889917226 cites W2124751168 @default.
• W2889917226 cites W2143205611 @default.
• W2889917226 cites W2149360962 @default.
• W2889917226 cites W2150987569 @default.
• W2889917226 cites W2152276494 @default.
• W2889917226 cites W2154197653 @default.
• W2889917226 cites W2155039674 @default.
• W2889917226 cites W2164659462 @default.
• W2889917226 cites W2278419621 @default.
• W2889917226 cites W2397429809 @default.
• W2889917226 cites W2506310782 @default.
• W2889917226 cites W2638004687 @default.
• W2889917226 cites W2748384357 @default.
• W2889917226 cites W2765116378 @default.
• W2889917226 cites W2884898260 @default.
• W2889917226 doi "https://doi.org/10.1016/j.jsb.2018.09.005" @default.
• W2889917226 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30237066" @default.
• W2889917226 hasPublicationYear "2018" @default.
• W2889917226 type Work @default.
• W2889917226 sameAs 2889917226 @default.
• W2889917226 citedByCount "12" @default.
• W2889917226 countsByYear W28899172262018 @default.
• W2889917226 countsByYear W28899172262019 @default.
• W2889917226 countsByYear W28899172262020 @default.
• W2889917226 countsByYear W28899172262021 @default.
• W2889917226 countsByYear W28899172262022 @default.
• W2889917226 countsByYear W28899172262023 @default.
• W2889917226 crossrefType "journal-article" @default.
• W2889917226 hasAuthorship W2889917226A5055564291 @default.
• W2889917226 hasAuthorship W2889917226A5071083916 @default.
• W2889917226 hasBestOaLocation W28899172261 @default.
• W2889917226 hasConcept C107457646 @default.
• W2889917226 hasConcept C11413529 @default.
• W2889917226 hasConcept C115901376 @default.
• W2889917226 hasConcept C121332964 @default.
• W2889917226 hasConcept C124101348 @default.
• W2889917226 hasConcept C127413603 @default.
• W2889917226 hasConcept C138268822 @default.
• W2889917226 hasConcept C154945302 @default.
• W2889917226 hasConcept C170130773 @default.
• W2889917226 hasConcept C18051474 @default.
• W2889917226 hasConcept C185592680 @default.
• W2889917226 hasConcept C189474733 @default.
• W2889917226 hasConcept C194778546 @default.
• W2889917226 hasConcept C199360897 @default.
• W2889917226 hasConcept C20556612 @default.
• W2889917226 hasConcept C20702342 @default.
• W2889917226 hasConcept C41008148 @default.
• W2889917226 hasConcept C47701112 @default.
• W2889917226 hasConcept C55493867 @default.
• W2889917226 hasConcept C62520636 @default.
• W2889917226 hasConcept C78519656 @default.
• W2889917226 hasConcept C82714645 @default.
• W2889917226 hasConceptScore W2889917226C107457646 @default.
• W2889917226 hasConceptScore W2889917226C11413529 @default.
• W2889917226 hasConceptScore W2889917226C115901376 @default.
• W2889917226 hasConceptScore W2889917226C121332964 @default.
• W2889917226 hasConceptScore W2889917226C124101348 @default.
• W2889917226 hasConceptScore W2889917226C127413603 @default.
• W2889917226 hasConceptScore W2889917226C138268822 @default.
• W2889917226 hasConceptScore W2889917226C154945302 @default.
• W2889917226 hasConceptScore W2889917226C170130773 @default.
• W2889917226 hasConceptScore W2889917226C18051474 @default.
• W2889917226 hasConceptScore W2889917226C185592680 @default.
• W2889917226 hasConceptScore W2889917226C189474733 @default.
• W2889917226 hasConceptScore W2889917226C194778546 @default.
• W2889917226 hasConceptScore W2889917226C199360897 @default.
• W2889917226 hasConceptScore W2889917226C20556612 @default.
• W2889917226 hasConceptScore W2889917226C20702342 @default.
• W2889917226 hasConceptScore W2889917226C41008148 @default.
• W2889917226 hasConceptScore W2889917226C47701112 @default.
• W2889917226 hasConceptScore W2889917226C55493867 @default.
• W2889917226 hasConceptScore W2889917226C62520636 @default.
• W2889917226 hasConceptScore W2889917226C78519656 @default.
• W2889917226 hasConceptScore W2889917226C82714645 @default.

• next