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- W2890031722 abstract "SUMMARY Posttranslational modifications (PTMs) of proteins are central in any kind of cellular signaling. Modern mass spectrometry technologies enable comprehensive identification and quantification of various PTMs. Given the increased number and types of mapped protein modifications, a database is necessary that simultaneouly integrates and compares site-specific information for different PTMs, especially in plants for which the available PTM data are poorly catalogued. Here, we present the Plant PTM Viewer ( http://www.psb.ugent.be/PlantPTMViewer ), an integrative PTM resource that comprises approximately 200,000 PTM sites for 17 types of protein modifications in plant proteins from five different species. The Plant PTM Viewer provides the user with a protein sequence overview in which the experimentally evidenced PTMs are highlighted together with functional protein domains or active site residues. The PTM sequence search tool can query PTM combinations in specific protein sequences, whereas the PTM BLAST tool searches for modified protein sequences to detect conserved PTMs in homologous sequences. Taken together, these tools facilitate to assume the role and potential interplay of PTMs in specific proteins or within a broader systems biology context. The Plant PTM Viewer is an open repository that allows submission of mass spectrometry-based PTM data to remain at pace with future PTM plant studies." @default.
- W2890031722 created "2018-09-27" @default.
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- W2890031722 date "2018-09-13" @default.
- W2890031722 modified "2023-09-27" @default.
- W2890031722 title "The Plant PTM Viewer, a central resource exploring plant protein modifications. From site-seeing to protein function" @default.
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- W2890031722 doi "https://doi.org/10.1101/415802" @default.
- W2890031722 hasPublicationYear "2018" @default.
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