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• W2890105461 abstract "Dissecting the gut-brain axis It is generally believed that cells in the gut transduce sensory information through the paracrine action of hormones. Kaelberer et al. found that, in addition to the well-described classical paracrine transduction, enteroendocrine cells also form fast, excitatory synapses with vagal afferents (see the Perspective by Hoffman and Lumpkin). This more direct circuit for gut-brain signaling uses glutamate as a neurotransmitter. Thus, sensory cues that stimulate the gut could potentially be manipulated to influence specific brain functions and behavior, including those linked to food choices. Science , this issue p. eaat5236 ; see also p. 1203" @default.
• W2890105461 created "2018-09-27" @default.
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• W2890105461 date "2018-09-21" @default.
• W2890105461 modified "2023-10-17" @default.
• W2890105461 title "A gut-brain neural circuit for nutrient sensory transduction" @default.
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• W2890105461 doi "https://doi.org/10.1126/science.aat5236" @default.
• W2890105461 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6417812" @default.
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