Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890122982> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2890122982 endingPage "152" @default.
- W2890122982 startingPage "152" @default.
- W2890122982 abstract "Objective: To evaluate the acute toxicity effect of metribuzin at low dose on liver of mother rabbits and its fetus. Methods: Pregnant female rabbits Oryctolagus cuniculus were divided into three groups (n=5). The first group of non-treated pregnancy rabbits served as control; the second group of pregnancy rabbits were treated with 1/100 LD50 of metribuzin and the third group of pregnancy rabbits were treated with 1/50 LD50 of metribuzin. Metribuzin was added in their drinking water for 60 d before and during pregnancy. Levels of liver malondialdehyde, liver glutathione S transferase, serum glutamic oxalacetic transaminase and serum glutamic- pyruvic transaminase were determined. Liver reduced glutathione level was also determined by a colorimetric method. And hepatic homogenate was analyzed by HPLC analysis to determine the existence of traces of metribuzin. Results: Results revealed a significant increase in level of liver malondialdehyde, glutathione S transferase, serum glutamic oxalacetic transaminase and serum glutamic-pyruvic transaminase activities in mother and fetuses rabbits of both metribuzin treatment groups as compared to the control group. However the level of reduced glutathione was decreased in mother and fetuses rabbits of both groups treated with metribuzin compared to control group. Also, the results obtained by HPLC technique showed the presence of trace metribuzin in liver cells of mothers and fetuses rabbits of the both metribuzin treated groups. Conclusions: In conclusion, this study shows that exposure to metribuzin at low concentrations causes a acute toxicity in liver of mother rabbits and its fetus, also the trace of the metribuzin detected in the liver is the origin of possible malformation of the fetuses or abortion of the rabbits." @default.
- W2890122982 created "2018-09-27" @default.
- W2890122982 creator A5010564397 @default.
- W2890122982 creator A5027396690 @default.
- W2890122982 creator A5056328079 @default.
- W2890122982 date "2018-01-01" @default.
- W2890122982 modified "2023-10-08" @default.
- W2890122982 title "Triazinone herbicide metribuzin induced acute liver injury: A study of animal model" @default.
- W2890122982 cites W4243227845 @default.
- W2890122982 doi "https://doi.org/10.4103/2221-6189.241016" @default.
- W2890122982 hasPublicationYear "2018" @default.
- W2890122982 type Work @default.
- W2890122982 sameAs 2890122982 @default.
- W2890122982 citedByCount "7" @default.
- W2890122982 countsByYear W28901229822020 @default.
- W2890122982 countsByYear W28901229822021 @default.
- W2890122982 countsByYear W28901229822022 @default.
- W2890122982 countsByYear W28901229822023 @default.
- W2890122982 crossrefType "journal-article" @default.
- W2890122982 hasAuthorship W2890122982A5010564397 @default.
- W2890122982 hasAuthorship W2890122982A5027396690 @default.
- W2890122982 hasAuthorship W2890122982A5056328079 @default.
- W2890122982 hasBestOaLocation W28901229821 @default.
- W2890122982 hasConcept C126322002 @default.
- W2890122982 hasConcept C134018914 @default.
- W2890122982 hasConcept C147273371 @default.
- W2890122982 hasConcept C172680121 @default.
- W2890122982 hasConcept C181199279 @default.
- W2890122982 hasConcept C2776151105 @default.
- W2890122982 hasConcept C2776877979 @default.
- W2890122982 hasConcept C2778401633 @default.
- W2890122982 hasConcept C2779234561 @default.
- W2890122982 hasConcept C2779315688 @default.
- W2890122982 hasConcept C29730261 @default.
- W2890122982 hasConcept C42407357 @default.
- W2890122982 hasConcept C538909803 @default.
- W2890122982 hasConcept C54355233 @default.
- W2890122982 hasConcept C55493867 @default.
- W2890122982 hasConcept C6557445 @default.
- W2890122982 hasConcept C71924100 @default.
- W2890122982 hasConcept C86803240 @default.
- W2890122982 hasConceptScore W2890122982C126322002 @default.
- W2890122982 hasConceptScore W2890122982C134018914 @default.
- W2890122982 hasConceptScore W2890122982C147273371 @default.
- W2890122982 hasConceptScore W2890122982C172680121 @default.
- W2890122982 hasConceptScore W2890122982C181199279 @default.
- W2890122982 hasConceptScore W2890122982C2776151105 @default.
- W2890122982 hasConceptScore W2890122982C2776877979 @default.
- W2890122982 hasConceptScore W2890122982C2778401633 @default.
- W2890122982 hasConceptScore W2890122982C2779234561 @default.
- W2890122982 hasConceptScore W2890122982C2779315688 @default.
- W2890122982 hasConceptScore W2890122982C29730261 @default.
- W2890122982 hasConceptScore W2890122982C42407357 @default.
- W2890122982 hasConceptScore W2890122982C538909803 @default.
- W2890122982 hasConceptScore W2890122982C54355233 @default.
- W2890122982 hasConceptScore W2890122982C55493867 @default.
- W2890122982 hasConceptScore W2890122982C6557445 @default.
- W2890122982 hasConceptScore W2890122982C71924100 @default.
- W2890122982 hasConceptScore W2890122982C86803240 @default.
- W2890122982 hasIssue "4" @default.
- W2890122982 hasLocation W28901229821 @default.
- W2890122982 hasLocation W28901229822 @default.
- W2890122982 hasOpenAccess W2890122982 @default.
- W2890122982 hasPrimaryLocation W28901229821 @default.
- W2890122982 hasRelatedWork W1986731363 @default.
- W2890122982 hasRelatedWork W2033864802 @default.
- W2890122982 hasRelatedWork W2094433083 @default.
- W2890122982 hasRelatedWork W2323087543 @default.
- W2890122982 hasRelatedWork W2518076529 @default.
- W2890122982 hasRelatedWork W2790254601 @default.
- W2890122982 hasRelatedWork W2792438796 @default.
- W2890122982 hasRelatedWork W2944873306 @default.
- W2890122982 hasRelatedWork W2947783453 @default.
- W2890122982 hasRelatedWork W4283815103 @default.
- W2890122982 hasVolume "7" @default.
- W2890122982 isParatext "false" @default.
- W2890122982 isRetracted "false" @default.
- W2890122982 magId "2890122982" @default.
- W2890122982 workType "article" @default.