Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890127217> ?p ?o ?g. }
- W2890127217 endingPage "126" @default.
- W2890127217 startingPage "115" @default.
- W2890127217 abstract "Sertoli cells were treated with 0, 20, 40, 60 and 80 μg/L of MC-LR to investigate its toxic effects, mechanism of action and immune response of the cells. Our results revealed that treatment containing 20 μg/L of MC-LR was non-toxic to the cells. Treatments containing 40, 60 and 80 μg/L of MC-LR reduced the cell viability, induced nuclear morphological changes and downregulated the blood-testis barrier constituent proteins within 48 h after treatment. The toll-like receptor 4 (TLR4) and nuclear factor-kappaB (NF-kB) were activated and significantly (P < 0.05) upregulated in cells treated with 40, 60 and 80 μg/L of MC-LR compared to the control. The pro-inflammatory cytokines were upregulated within 48 h after treatment. However commencing from 72 h, upregulation of anti-inflammatory cytokines and expression of blood-testis barrier constituent proteins was observed. This study indicates that MC-LR induced inflammatory response in bovine Sertoli cell via activation of TLR4/NF-kB signaling pathway." @default.
- W2890127217 created "2018-09-27" @default.
- W2890127217 creator A5002069535 @default.
- W2890127217 creator A5013038112 @default.
- W2890127217 creator A5041100767 @default.
- W2890127217 creator A5043126622 @default.
- W2890127217 creator A5050852420 @default.
- W2890127217 creator A5053658255 @default.
- W2890127217 creator A5054441443 @default.
- W2890127217 creator A5056332977 @default.
- W2890127217 creator A5090898144 @default.
- W2890127217 date "2018-10-01" @default.
- W2890127217 modified "2023-10-16" @default.
- W2890127217 title "Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway" @default.
- W2890127217 cites W1489771292 @default.
- W2890127217 cites W1520133154 @default.
- W2890127217 cites W1523768703 @default.
- W2890127217 cites W1532919526 @default.
- W2890127217 cites W1655860314 @default.
- W2890127217 cites W1964589272 @default.
- W2890127217 cites W1968714545 @default.
- W2890127217 cites W1971536244 @default.
- W2890127217 cites W1972332133 @default.
- W2890127217 cites W1973343064 @default.
- W2890127217 cites W1974890191 @default.
- W2890127217 cites W1976001505 @default.
- W2890127217 cites W1993101448 @default.
- W2890127217 cites W1998169605 @default.
- W2890127217 cites W2002389652 @default.
- W2890127217 cites W2002556891 @default.
- W2890127217 cites W2003912126 @default.
- W2890127217 cites W2008981126 @default.
- W2890127217 cites W2009858209 @default.
- W2890127217 cites W2012443958 @default.
- W2890127217 cites W2012759377 @default.
- W2890127217 cites W2015773179 @default.
- W2890127217 cites W2018866981 @default.
- W2890127217 cites W2024979614 @default.
- W2890127217 cites W2026492207 @default.
- W2890127217 cites W2029453489 @default.
- W2890127217 cites W2032158597 @default.
- W2890127217 cites W2033893811 @default.
- W2890127217 cites W2038372048 @default.
- W2890127217 cites W2039926711 @default.
- W2890127217 cites W2042355470 @default.
- W2890127217 cites W2042603980 @default.
- W2890127217 cites W2056291584 @default.
- W2890127217 cites W2059564273 @default.
- W2890127217 cites W2062461025 @default.
- W2890127217 cites W2063315098 @default.
- W2890127217 cites W2064680722 @default.
- W2890127217 cites W2066306511 @default.
- W2890127217 cites W2071415655 @default.
- W2890127217 cites W2074685588 @default.
- W2890127217 cites W2076588832 @default.
- W2890127217 cites W2088373848 @default.
- W2890127217 cites W2091285777 @default.
- W2890127217 cites W2093750841 @default.
- W2890127217 cites W2121276791 @default.
- W2890127217 cites W2122039020 @default.
- W2890127217 cites W2133449490 @default.
- W2890127217 cites W2135113543 @default.
- W2890127217 cites W2136306240 @default.
- W2890127217 cites W2139248293 @default.
- W2890127217 cites W2140616490 @default.
- W2890127217 cites W2154262496 @default.
- W2890127217 cites W2155153491 @default.
- W2890127217 cites W2158211144 @default.
- W2890127217 cites W2161789287 @default.
- W2890127217 cites W2164967582 @default.
- W2890127217 cites W2183565932 @default.
- W2890127217 cites W2280149859 @default.
- W2890127217 cites W2280955573 @default.
- W2890127217 cites W2320450567 @default.
- W2890127217 cites W2562474273 @default.
- W2890127217 cites W2741446350 @default.
- W2890127217 cites W2788422364 @default.
- W2890127217 cites W315927324 @default.
- W2890127217 doi "https://doi.org/10.1016/j.etap.2018.09.001" @default.
- W2890127217 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30212741" @default.
- W2890127217 hasPublicationYear "2018" @default.
- W2890127217 type Work @default.
- W2890127217 sameAs 2890127217 @default.
- W2890127217 citedByCount "25" @default.
- W2890127217 countsByYear W28901272172018 @default.
- W2890127217 countsByYear W28901272172019 @default.
- W2890127217 countsByYear W28901272172020 @default.
- W2890127217 countsByYear W28901272172021 @default.
- W2890127217 countsByYear W28901272172022 @default.
- W2890127217 countsByYear W28901272172023 @default.
- W2890127217 crossrefType "journal-article" @default.
- W2890127217 hasAuthorship W2890127217A5002069535 @default.
- W2890127217 hasAuthorship W2890127217A5013038112 @default.
- W2890127217 hasAuthorship W2890127217A5041100767 @default.
- W2890127217 hasAuthorship W2890127217A5043126622 @default.
- W2890127217 hasAuthorship W2890127217A5050852420 @default.
- W2890127217 hasAuthorship W2890127217A5053658255 @default.
- W2890127217 hasAuthorship W2890127217A5054441443 @default.