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• W2890129736 abstract "<br><b>Background/Aims:</b> To compare water exchange (WE) method with conventional air insufflation (AI) method for colonoscopy, evaluating the technical quality, screening efficacy, and patients' acceptance.<br><b>Materials and Methods:</b> Electronic databases were systematically searched for randomized controlled trials comparing WE colonoscopy with AI colonoscopy. The pooled data of procedure-associated and patient-related outcomes were assessed, using the weighted mean difference (WMD) with 95% confidence interval (CI) for continuous variables and relative risk (RR) with 95% CI for dichotomous variables, respectively.<br><b>Results:</b> A total of 13 studies involving 7056 patients were included. The cecum intubation rate was similar between WE and AI methods (RR = 1.01, 95% CI = 0.99–1.02,<i>P</i> = 0.37); however, a significantly longer cecum intubation time was shown in WE group (WMD = 1.56, 95% CI = 0.75–2.37,<i>P</i> = 0.002). Compared with AI, WE was associated with a higher risk of adenoma detection rate (ADR) (RR = 1.28, 95% CI = 1.18–1.38,<i>P</i> < 0.00001) and polyp detection rate (PDR) (RR = 1.30, 95% CI = 1.21–1.39,<i>P</i> < 0.00001). Patients in WE group experienced significantly less maximum pain score (WMD = −1.99, 95% CI = −2.68 to −1.30,<i>P</i> < 0.00001) and less requested on-demand sedation (RR = 0.58, 95% CI = 0.44–0.77,<i>P</i> = 0.0002). Likewise, they also experienced less abdominal compression (RR = 0.62, 95% CI = 0.51-0.74,<i>P</i> < 0.00001) and reposition (RR = 0.74, 95% CI = 0.63-0.86,<i>P</i> = 0.0001). Moreover, patients' willingness to repeat colonoscopy was significantly greater for WE (RR = 1.14, 95% CI = 1.07–1.21,<i>P</i> < 0.0001).<br><b>Conclusion:</b> This meta-analysis confirmed that WE method could significantly increase ADR/PDR and improve patients' acceptance of colonoscopy, while reducing the degree of pain and minimize the need for on-demand sedation and adjunct maneuvers, despite requiring more cecal intubation time.<br>" @default.
• W2890129736 created "2018-09-27" @default.
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• W2890129736 date "2018-01-01" @default.
• W2890129736 modified "2023-09-25" @default.
• W2890129736 title "Water exchange versus air insufflation for colonoscopy: A meta-analysis" @default.
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• W2890129736 doi "https://doi.org/10.4103/sjg.sjg_118_18" @default.
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