FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890143300> ?p ?o ?g. }

• W2890143300 endingPage "567" @default.
• W2890143300 startingPage "544" @default.
• W2890143300 abstract "The &#946;-lactams constitute a well-known class of compounds having tremendous biological significance. Besides being a motif of biological interest, they serve as versatile synthons in organic chemistry. In fact, their easy accessibility in the laboratory by several methods combined with inherent reactivity of the &#946; -lactam ring due to ring-strain places it among the most sought for substrate in the arsenal of synthetic organic chemists. Several chemical reagents, heat, and light promote its ring-opening, ring-expansions and rearrangement reactions yielding a wide variety of biologically relevant nitrogen-containing acyclic and heterocyclic compounds. In recent years, the reactivity of differently functionalized &#946;-lactam rings towards diverse kinds of reagents has been investigated. These investigations exploit selective bond cleavage of the &#946;-lactam nucleus via N1-C2, C3- C4, C2-C3 or N1-C4 bond cleavage using simple reagents. The reduction of amide carbonyl group, thionation, and pyrolysis/photolysis have also been explored. These investigations have led to the discovery of many easy synthetic methods for biologically important classes of compounds such as &#946;-amino acids, &#946;-amino esters, amino sugars, amino alcohols, peptides, azetidines, and other heterocyclic compounds. This article discusses the advances made in the studies on the reactivity of &#946;- lactam ring during the last ten years." @default.
• W2890143300 created "2018-09-27" @default.
• W2890143300 creator A5061098895 @default.
• W2890143300 date "2019-08-27" @default.
• W2890143300 modified "2023-09-27" @default.
• W2890143300 title "Recent Progress in Chemistry of β-Lactams" @default.
• W2890143300 cites W1779381586 @default.
• W2890143300 cites W1905601466 @default.
• W2890143300 cites W1963624760 @default.
• W2890143300 cites W1964008931 @default.
• W2890143300 cites W1964684995 @default.
• W2890143300 cites W1965804292 @default.
• W2890143300 cites W1985410759 @default.
• W2890143300 cites W1986334901 @default.
• W2890143300 cites W1986977795 @default.
• W2890143300 cites W1987017190 @default.
• W2890143300 cites W1996652654 @default.
• W2890143300 cites W1997023823 @default.
• W2890143300 cites W1997704870 @default.
• W2890143300 cites W1999556008 @default.
• W2890143300 cites W2005813132 @default.
• W2890143300 cites W2008568000 @default.
• W2890143300 cites W2025177611 @default.
• W2890143300 cites W2028258554 @default.
• W2890143300 cites W2032526995 @default.
• W2890143300 cites W2042034828 @default.
• W2890143300 cites W2042536756 @default.
• W2890143300 cites W2051434988 @default.
• W2890143300 cites W2054998268 @default.
• W2890143300 cites W2062652881 @default.
• W2890143300 cites W2074958024 @default.
• W2890143300 cites W2077318961 @default.
• W2890143300 cites W2082641556 @default.
• W2890143300 cites W2084418065 @default.
• W2890143300 cites W2088021352 @default.
• W2890143300 cites W2088822421 @default.
• W2890143300 cites W2099106434 @default.
• W2890143300 cites W2116408528 @default.
• W2890143300 cites W2118757087 @default.
• W2890143300 cites W2133723384 @default.
• W2890143300 cites W2143112544 @default.
• W2890143300 cites W2146957556 @default.
• W2890143300 cites W2147904068 @default.
• W2890143300 cites W2153072013 @default.
• W2890143300 cites W2154785180 @default.
• W2890143300 cites W2163403661 @default.
• W2890143300 cites W2203350573 @default.
• W2890143300 cites W2215466160 @default.
• W2890143300 cites W2252897518 @default.
• W2890143300 cites W2273920006 @default.
• W2890143300 cites W2346691849 @default.
• W2890143300 cites W2405402660 @default.
• W2890143300 cites W2408549974 @default.
• W2890143300 cites W2522173038 @default.
• W2890143300 cites W2535976436 @default.
• W2890143300 cites W2586013143 @default.
• W2890143300 cites W2752219718 @default.
• W2890143300 cites W2772467871 @default.
• W2890143300 cites W2784047994 @default.
• W2890143300 cites W2916012205 @default.
• W2890143300 cites W2949086900 @default.
• W2890143300 cites W2949261461 @default.
• W2890143300 cites W2949451043 @default.
• W2890143300 cites W2950497894 @default.
• W2890143300 cites W2950716575 @default.
• W2890143300 cites W2951018223 @default.
• W2890143300 cites W2951055797 @default.
• W2890143300 cites W2951516599 @default.
• W2890143300 cites W2951629560 @default.
• W2890143300 cites W2951646900 @default.
• W2890143300 cites W2952300931 @default.
• W2890143300 cites W2952415840 @default.
• W2890143300 cites W2952727300 @default.
• W2890143300 cites W2953342346 @default.
• W2890143300 cites W2953388004 @default.
• W2890143300 cites W2089861217 @default.
• W2890143300 doi "https://doi.org/10.2174/1570193x15666180914165303" @default.
• W2890143300 hasPublicationYear "2019" @default.
• W2890143300 type Work @default.
• W2890143300 sameAs 2890143300 @default.
• W2890143300 citedByCount "10" @default.
• W2890143300 countsByYear W28901433002016 @default.
• W2890143300 countsByYear W28901433002020 @default.
• W2890143300 countsByYear W28901433002021 @default.
• W2890143300 countsByYear W28901433002022 @default.
• W2890143300 countsByYear W28901433002023 @default.
• W2890143300 crossrefType "journal-article" @default.
• W2890143300 hasAuthorship W2890143300A5061098895 @default.
• W2890143300 hasConcept C114373084 @default.
• W2890143300 hasConcept C142724271 @default.
• W2890143300 hasConcept C161790260 @default.
• W2890143300 hasConcept C178790620 @default.
• W2890143300 hasConcept C181199279 @default.
• W2890143300 hasConcept C185592680 @default.
• W2890143300 hasConcept C202751555 @default.
• W2890143300 hasConcept C204787440 @default.
• W2890143300 hasConcept C21951064 @default.
• W2890143300 hasConcept C2776131168 @default.

• next