Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890163039> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2890163039 abstract "The distribution of active pharmaceutical ingredients (APIs) in prescription medicines for human consumption in Japan was estimated using the public database of the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB). From the latest NDB, 2058 APIs were identified, and the prescription weight exceeded 1 tonne/year for 711 APIs. Of these, 298 APIs were selected for further analysis after removing 413 APIs that were not covered by current environmental risk assessment (ERA) directives or were combination products. Among the 298 APIs, 43 were relatively newly branded APIs that have been available on the Japanese market since 2001 or later and have no generic drugs, and only 5 of the branded APIs are used by more than 1% of the population. When prescription data from the 47 prefectures in Japan were analyzed, prescription weights for 257 of the 298 APIs were the highest in Tokyo, probably because of its large population. Though it has both advantages and limitations, this novel method based on a non-profit public database can provide a transparent, unbiased and cost-effective solution for the estimation of the environmental exposure of generic and branded human medicines distributed with prescriptions in Japan." @default.
- W2890163039 created "2018-09-27" @default.
- W2890163039 creator A5028209482 @default.
- W2890163039 creator A5031249539 @default.
- W2890163039 creator A5037201251 @default.
- W2890163039 creator A5051234043 @default.
- W2890163039 creator A5063312716 @default.
- W2890163039 creator A5084805336 @default.
- W2890163039 date "2018-11-01" @default.
- W2890163039 modified "2023-09-23" @default.
- W2890163039 title "Estimation of total prescription weights of active pharmaceutical ingredients in human medicines based on a public database for environmental risk assessment in Japan" @default.
- W2890163039 cites W1516645853 @default.
- W2890163039 cites W1971503506 @default.
- W2890163039 cites W1994812955 @default.
- W2890163039 cites W2017839381 @default.
- W2890163039 cites W2065182727 @default.
- W2890163039 cites W2078146503 @default.
- W2890163039 cites W2082234704 @default.
- W2890163039 cites W2110208419 @default.
- W2890163039 cites W2144409727 @default.
- W2890163039 cites W2436109817 @default.
- W2890163039 cites W3167944398 @default.
- W2890163039 doi "https://doi.org/10.1016/j.yrtph.2018.09.014" @default.
- W2890163039 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30223071" @default.
- W2890163039 hasPublicationYear "2018" @default.
- W2890163039 type Work @default.
- W2890163039 sameAs 2890163039 @default.
- W2890163039 citedByCount "3" @default.
- W2890163039 countsByYear W28901630392020 @default.
- W2890163039 countsByYear W28901630392021 @default.
- W2890163039 crossrefType "journal-article" @default.
- W2890163039 hasAuthorship W2890163039A5028209482 @default.
- W2890163039 hasAuthorship W2890163039A5031249539 @default.
- W2890163039 hasAuthorship W2890163039A5037201251 @default.
- W2890163039 hasAuthorship W2890163039A5051234043 @default.
- W2890163039 hasAuthorship W2890163039A5063312716 @default.
- W2890163039 hasAuthorship W2890163039A5084805336 @default.
- W2890163039 hasConcept C127413603 @default.
- W2890163039 hasConcept C138816342 @default.
- W2890163039 hasConcept C144024400 @default.
- W2890163039 hasConcept C144133560 @default.
- W2890163039 hasConcept C159110408 @default.
- W2890163039 hasConcept C162324750 @default.
- W2890163039 hasConcept C175444787 @default.
- W2890163039 hasConcept C181622380 @default.
- W2890163039 hasConcept C201995342 @default.
- W2890163039 hasConcept C2426938 @default.
- W2890163039 hasConcept C2908647359 @default.
- W2890163039 hasConcept C2987857752 @default.
- W2890163039 hasConcept C30772137 @default.
- W2890163039 hasConcept C36289849 @default.
- W2890163039 hasConcept C41008148 @default.
- W2890163039 hasConcept C71924100 @default.
- W2890163039 hasConcept C77088390 @default.
- W2890163039 hasConcept C96250715 @default.
- W2890163039 hasConcept C98274493 @default.
- W2890163039 hasConcept C99454951 @default.
- W2890163039 hasConceptScore W2890163039C127413603 @default.
- W2890163039 hasConceptScore W2890163039C138816342 @default.
- W2890163039 hasConceptScore W2890163039C144024400 @default.
- W2890163039 hasConceptScore W2890163039C144133560 @default.
- W2890163039 hasConceptScore W2890163039C159110408 @default.
- W2890163039 hasConceptScore W2890163039C162324750 @default.
- W2890163039 hasConceptScore W2890163039C175444787 @default.
- W2890163039 hasConceptScore W2890163039C181622380 @default.
- W2890163039 hasConceptScore W2890163039C201995342 @default.
- W2890163039 hasConceptScore W2890163039C2426938 @default.
- W2890163039 hasConceptScore W2890163039C2908647359 @default.
- W2890163039 hasConceptScore W2890163039C2987857752 @default.
- W2890163039 hasConceptScore W2890163039C30772137 @default.
- W2890163039 hasConceptScore W2890163039C36289849 @default.
- W2890163039 hasConceptScore W2890163039C41008148 @default.
- W2890163039 hasConceptScore W2890163039C71924100 @default.
- W2890163039 hasConceptScore W2890163039C77088390 @default.
- W2890163039 hasConceptScore W2890163039C96250715 @default.
- W2890163039 hasConceptScore W2890163039C98274493 @default.
- W2890163039 hasConceptScore W2890163039C99454951 @default.
- W2890163039 hasLocation W28901630391 @default.
- W2890163039 hasLocation W28901630392 @default.
- W2890163039 hasOpenAccess W2890163039 @default.
- W2890163039 hasPrimaryLocation W28901630391 @default.
- W2890163039 hasRelatedWork W1972196647 @default.
- W2890163039 hasRelatedWork W1998713624 @default.
- W2890163039 hasRelatedWork W2005534053 @default.
- W2890163039 hasRelatedWork W2013487920 @default.
- W2890163039 hasRelatedWork W2014687562 @default.
- W2890163039 hasRelatedWork W2139290821 @default.
- W2890163039 hasRelatedWork W2466759857 @default.
- W2890163039 hasRelatedWork W2985973419 @default.
- W2890163039 hasRelatedWork W2989666486 @default.
- W2890163039 hasRelatedWork W34506600 @default.
- W2890163039 isParatext "false" @default.
- W2890163039 isRetracted "false" @default.
- W2890163039 magId "2890163039" @default.
- W2890163039 workType "article" @default.