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• W2890170851 abstract "Tomato consumption has been recently associated with a reduced incidence of cardiovascular disease (CVD). The aim of this study was to test whether a seven-day period of tomato paste purèe (tomato paste, TP) supplementation could improve some haemodynamic parameters in healthy volunteers before and after a standardized fat meal (FM). Methods and results: Nineteen healthy male volunteers participated in a randomized, single-blind (operator) crossover study. Participants maintained low fiber diets (LFD) during the study periods. They were randomized either to a LFD and TP arm (80 g of TP/day) for seven-days, or to a control arm (LFD-only) with a two-week washout period. Flow Mediated Dilatation and other morpho-functional vascular indices were measured by ultrasound. Stiffness Index and Reflection Index were estimated by digital photo-plethysmography. All these parameters were measured one h before and two and 3.5 h after the FM. The difference in Stiffness Index was increased in the LFD and TP + FM-arm, as compared to the LFD-only + FM arm at both two and 3.5 h points. After the FM, in both arms, at two h, we observed a reduction in the Reflection Index and an increase in heart rate. Interestingly, only in the LFD and TP + FM-arm, some haemodynamic changes were detectable at two h; notably, there was an increase in brachial artery diameter and a reduction in diastolic blood pressure (BP). Conclusions: TP has no effect on Flow Mediated Dilatation but acutely modifies some haemodynamic parameters triggered by FM, suggesting possible haemodynamic beneficial effects in people consuming tomatoes." @default.
• W2890170851 created "2018-09-27" @default.
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• W2890170851 date "2018-09-15" @default.
• W2890170851 modified "2023-09-26" @default.
• W2890170851 title "Positive Effects of Tomato Paste on Vascular Function After a Fat Meal in Male Healthy Subjects" @default.
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• W2890170851 doi "https://doi.org/10.3390/nu10091310" @default.
• W2890170851 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6163719" @default.
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• W2890170851 hasPublicationYear "2018" @default.
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