Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890178435> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W2890178435 endingPage "267" @default.
- W2890178435 startingPage "261" @default.
- W2890178435 abstract "Sinonasal disease is a common feature of cystic fibrosis (CF) and can cause significant morbidity in these patients. Our objective was to determine if CF individuals with concomitant nasal polyposis (NP) express a unique profile of inflammation and if so, whether these inflammatory cytokine mediators have predictive value in identifying these individuals for prompt management by an Otolaryngologist.Nasal lavage samples and clinical outcomes of disease severity were obtained from thirty-eight pediatric CF individuals. Participants were subdivided based on the presence or absence of NP. Nasal lavage samples were analyzed on a panel of seventeen cytokine targets using a Bio-Plex Luminex assay. A Perl Permutation test with correction for multiple hypotheses was performed to identify uniquely expressed cytokines between CF individuals with NP (CFwNP) and those without (CFsNP).Thirty-five patients were included in the analysis. Cytokines IL-13 and GM-CSF were uniquely expressed in the CFwNP group when compared to the CFsNP group. Logistic regression analysis demonstrated a significant association of IL-13 with NP.In children diagnosed with CF, the level of IL-13 in nasal lavage samples could potentially serve as a non-invasive clinical tool in predicting NP in this population, and a target for future immunotherapy." @default.
- W2890178435 created "2018-09-27" @default.
- W2890178435 creator A5017249382 @default.
- W2890178435 creator A5020386193 @default.
- W2890178435 creator A5037758035 @default.
- W2890178435 creator A5045196107 @default.
- W2890178435 creator A5085141873 @default.
- W2890178435 date "2018-09-01" @default.
- W2890178435 modified "2023-10-12" @default.
- W2890178435 title "The presence of Interleukin-13 in nasal lavage may be a predictor of nasal polyposis in pediatric patients with cystic fibrosis" @default.
- W2890178435 doi "https://doi.org/10.4193/rhin17.007" @default.
- W2890178435 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29561922" @default.
- W2890178435 hasPublicationYear "2018" @default.
- W2890178435 type Work @default.
- W2890178435 sameAs 2890178435 @default.
- W2890178435 citedByCount "5" @default.
- W2890178435 countsByYear W28901784352018 @default.
- W2890178435 countsByYear W28901784352020 @default.
- W2890178435 countsByYear W28901784352022 @default.
- W2890178435 countsByYear W28901784352023 @default.
- W2890178435 crossrefType "journal-article" @default.
- W2890178435 hasAuthorship W2890178435A5017249382 @default.
- W2890178435 hasAuthorship W2890178435A5020386193 @default.
- W2890178435 hasAuthorship W2890178435A5037758035 @default.
- W2890178435 hasAuthorship W2890178435A5045196107 @default.
- W2890178435 hasAuthorship W2890178435A5085141873 @default.
- W2890178435 hasBestOaLocation W28901784351 @default.
- W2890178435 hasConcept C108516343 @default.
- W2890178435 hasConcept C126322002 @default.
- W2890178435 hasConcept C141071460 @default.
- W2890178435 hasConcept C151956035 @default.
- W2890178435 hasConcept C203014093 @default.
- W2890178435 hasConcept C207480886 @default.
- W2890178435 hasConcept C2776938444 @default.
- W2890178435 hasConcept C2778690821 @default.
- W2890178435 hasConcept C2779134260 @default.
- W2890178435 hasConcept C2908647359 @default.
- W2890178435 hasConcept C2909814679 @default.
- W2890178435 hasConcept C32046619 @default.
- W2890178435 hasConcept C71924100 @default.
- W2890178435 hasConcept C74172505 @default.
- W2890178435 hasConcept C90924648 @default.
- W2890178435 hasConcept C99454951 @default.
- W2890178435 hasConceptScore W2890178435C108516343 @default.
- W2890178435 hasConceptScore W2890178435C126322002 @default.
- W2890178435 hasConceptScore W2890178435C141071460 @default.
- W2890178435 hasConceptScore W2890178435C151956035 @default.
- W2890178435 hasConceptScore W2890178435C203014093 @default.
- W2890178435 hasConceptScore W2890178435C207480886 @default.
- W2890178435 hasConceptScore W2890178435C2776938444 @default.
- W2890178435 hasConceptScore W2890178435C2778690821 @default.
- W2890178435 hasConceptScore W2890178435C2779134260 @default.
- W2890178435 hasConceptScore W2890178435C2908647359 @default.
- W2890178435 hasConceptScore W2890178435C2909814679 @default.
- W2890178435 hasConceptScore W2890178435C32046619 @default.
- W2890178435 hasConceptScore W2890178435C71924100 @default.
- W2890178435 hasConceptScore W2890178435C74172505 @default.
- W2890178435 hasConceptScore W2890178435C90924648 @default.
- W2890178435 hasConceptScore W2890178435C99454951 @default.
- W2890178435 hasIssue "3" @default.
- W2890178435 hasLocation W28901784351 @default.
- W2890178435 hasLocation W28901784352 @default.
- W2890178435 hasOpenAccess W2890178435 @default.
- W2890178435 hasPrimaryLocation W28901784351 @default.
- W2890178435 hasRelatedWork W2037128302 @default.
- W2890178435 hasRelatedWork W2067301453 @default.
- W2890178435 hasRelatedWork W2069164702 @default.
- W2890178435 hasRelatedWork W2079663038 @default.
- W2890178435 hasRelatedWork W2316367627 @default.
- W2890178435 hasRelatedWork W2334695114 @default.
- W2890178435 hasRelatedWork W2414453205 @default.
- W2890178435 hasRelatedWork W2947886151 @default.
- W2890178435 hasRelatedWork W3029629814 @default.
- W2890178435 hasRelatedWork W3207139836 @default.
- W2890178435 hasVolume "56" @default.
- W2890178435 isParatext "false" @default.
- W2890178435 isRetracted "false" @default.
- W2890178435 magId "2890178435" @default.
- W2890178435 workType "article" @default.