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- W2890182654 abstract "The present study analysis of drugs plays a major role in the development, manufacture andtherapeutic use of drug. Quantitative analysis of raw materials and the final productis necessary to ensure that they meet certain specifications and to ascertain theamount of each component in the final product.Standard analytical procedures for newly designed and synthesized drugs arenot available in any of the pharmacopoeias. So it becomes necessary to developnewer, accurate, specific, simple, easy to perform, reliable and economic analyticaltechniques for the estimation of the new drugs.This thesis deals with pantoprazole (PNP) and cinitapride (CNP).Pantoprazole has been recently included in Indian Pharmacopoeia – 2010.Cinitapride is a very new drug, launched in 2007 and is not official in any of thepharmacopoeias. It has been very recently added in drug bank in 2012. Thecombination of the two drugs has been launched in 2011.Extensive literature surveyreveals that only first derivative and HPTLC method for the determination ofpantoprazole (PNP) and cinitapride (CNP) has been reported. There is no evidencefor the estimation of PNP and CNP by UV-Visible spectrophotometry and RP-HPLC. CONCLUSION: The developed UV – Visible and RP-HPLC methods were found to be simple,precise, accurate and rapid methods for the analysis of Cinitapride andPantoprazole in its pure form and in its pharmaceutical dosage formulation.Thus, all the above adopted methods can be effectively used for the routineanalysis of Cinitapride and Pantoprazole in pharmaceutical dosage form.methods in bulk and in combined tablet dosage form. So, an attempt has beenmade is to develop a validated, simple, easy to perform, accurate, cost effectiveand rapid spectrophotometric methods for the estimation of CNP and PNP inbulk and combined oral dosage form." @default.
- W2890182654 created "2018-09-27" @default.
- W2890182654 creator A5028871733 @default.
- W2890182654 date "2012-05-01" @default.
- W2890182654 modified "2023-09-24" @default.
- W2890182654 title "Validated Method Development for the Quantification of Cinitapride and Pantoprazole by Spectrophotometry and RP-HPLC in Bulk and Oral Dosge form." @default.
- W2890182654 hasPublicationYear "2012" @default.
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