Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890198550> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2890198550 endingPage "8077" @default.
- W2890198550 startingPage "8070" @default.
- W2890198550 abstract "In this work, a novel combination of drug therapy and cryotherapy for tumor treatment was developed. Pluronic F127 modified with poly(acrylic acid) at two terminals (denoted as PAA-PF127-PAA) was used as carriers for doxorubicin (DOX) delivery. Due to the pH-sensitive property endowed by PAA, the DOX-loaded PAA-PF127-PAA micelles released DOX faster in the slightly acidic physiological environment of the tumor site than that in the neutral physiological environment. Three-group rats bearing Walker 256 carcinosarcoma were respectively treated with cryotherapy, combination of DOX-loaded micelles and cryotherapy, and saline injection to investigate the effect of the combined therapy. The apoptosis rate of TdT-mediated dUTP nick-end labeling (TUNEL) slices indicated that compared with cryotherapy alone, the DOX-loaded PAA-PF127-PAA micelles combining with cryotherapy showed increased apoptosis. Thus, the combination of drug therapy and cryotherapy can be used as an effective technique for tumor treatment." @default.
- W2890198550 created "2018-09-27" @default.
- W2890198550 creator A5012330077 @default.
- W2890198550 creator A5014299951 @default.
- W2890198550 creator A5020778756 @default.
- W2890198550 creator A5036062698 @default.
- W2890198550 creator A5052984792 @default.
- W2890198550 creator A5070286386 @default.
- W2890198550 date "2018-12-01" @default.
- W2890198550 modified "2023-09-23" @default.
- W2890198550 title "pH-Sensitive DOX-Loaded PAA-PF127-PAA Micelles Combined with Cryotherapy for Treating Walker 256 Carcinosarcoma in a Rat Model" @default.
- W2890198550 doi "https://doi.org/10.1166/jnn.2018.16409" @default.
- W2890198550 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30189921" @default.
- W2890198550 hasPublicationYear "2018" @default.
- W2890198550 type Work @default.
- W2890198550 sameAs 2890198550 @default.
- W2890198550 citedByCount "5" @default.
- W2890198550 countsByYear W28901985502019 @default.
- W2890198550 countsByYear W28901985502022 @default.
- W2890198550 countsByYear W28901985502023 @default.
- W2890198550 crossrefType "journal-article" @default.
- W2890198550 hasAuthorship W2890198550A5012330077 @default.
- W2890198550 hasAuthorship W2890198550A5014299951 @default.
- W2890198550 hasAuthorship W2890198550A5020778756 @default.
- W2890198550 hasAuthorship W2890198550A5036062698 @default.
- W2890198550 hasAuthorship W2890198550A5052984792 @default.
- W2890198550 hasAuthorship W2890198550A5070286386 @default.
- W2890198550 hasConcept C101335993 @default.
- W2890198550 hasConcept C11268172 @default.
- W2890198550 hasConcept C13965031 @default.
- W2890198550 hasConcept C141071460 @default.
- W2890198550 hasConcept C15920480 @default.
- W2890198550 hasConcept C159985019 @default.
- W2890198550 hasConcept C178790620 @default.
- W2890198550 hasConcept C184651966 @default.
- W2890198550 hasConcept C185592680 @default.
- W2890198550 hasConcept C192562407 @default.
- W2890198550 hasConcept C2776694085 @default.
- W2890198550 hasConcept C2780149145 @default.
- W2890198550 hasConcept C2780503075 @default.
- W2890198550 hasConcept C2781303535 @default.
- W2890198550 hasConcept C521977710 @default.
- W2890198550 hasConcept C71924100 @default.
- W2890198550 hasConcept C98274493 @default.
- W2890198550 hasConceptScore W2890198550C101335993 @default.
- W2890198550 hasConceptScore W2890198550C11268172 @default.
- W2890198550 hasConceptScore W2890198550C13965031 @default.
- W2890198550 hasConceptScore W2890198550C141071460 @default.
- W2890198550 hasConceptScore W2890198550C15920480 @default.
- W2890198550 hasConceptScore W2890198550C159985019 @default.
- W2890198550 hasConceptScore W2890198550C178790620 @default.
- W2890198550 hasConceptScore W2890198550C184651966 @default.
- W2890198550 hasConceptScore W2890198550C185592680 @default.
- W2890198550 hasConceptScore W2890198550C192562407 @default.
- W2890198550 hasConceptScore W2890198550C2776694085 @default.
- W2890198550 hasConceptScore W2890198550C2780149145 @default.
- W2890198550 hasConceptScore W2890198550C2780503075 @default.
- W2890198550 hasConceptScore W2890198550C2781303535 @default.
- W2890198550 hasConceptScore W2890198550C521977710 @default.
- W2890198550 hasConceptScore W2890198550C71924100 @default.
- W2890198550 hasConceptScore W2890198550C98274493 @default.
- W2890198550 hasIssue "12" @default.
- W2890198550 hasLocation W28901985501 @default.
- W2890198550 hasOpenAccess W2890198550 @default.
- W2890198550 hasPrimaryLocation W28901985501 @default.
- W2890198550 hasRelatedWork W1966257389 @default.
- W2890198550 hasRelatedWork W1977288803 @default.
- W2890198550 hasRelatedWork W2004432931 @default.
- W2890198550 hasRelatedWork W2006652605 @default.
- W2890198550 hasRelatedWork W2014679110 @default.
- W2890198550 hasRelatedWork W2027667545 @default.
- W2890198550 hasRelatedWork W2082093834 @default.
- W2890198550 hasRelatedWork W2363490744 @default.
- W2890198550 hasRelatedWork W2739365504 @default.
- W2890198550 hasRelatedWork W2891970541 @default.
- W2890198550 hasVolume "18" @default.
- W2890198550 isParatext "false" @default.
- W2890198550 isRetracted "false" @default.
- W2890198550 magId "2890198550" @default.
- W2890198550 workType "article" @default.