FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890224840> ?p ?o ?g. }

• W2890224840 endingPage "114" @default.
• W2890224840 startingPage "106" @default.
• W2890224840 abstract "Diabetes is associated with increased risk and worsened outcome of stroke. Previous studies showed that male diabetic animals had greater hemorrhagic transformation (HT), profound loss of cerebral vasculature, and poor behavioral outcomes after ischemic stroke induced by suture or embolic middle cerebral artery occlusion (MCAO). Females are protected from stroke until reaching the menopause age, but young females with diabetes have a higher risk of stroke and women account for the majority of stroke mortality. The current study postulated that diabetes is associated with greater vascular injury and exacerbated sensorimotor and cognitive outcome after stroke even in young female animals. Male and female control and diabetic animals were subjected to transient MCAO and followed for 3 or 14 days to assess the neurovascular injury and repair. The vascularization indices after stroke were lower in male diabetic animals with 90-min but not 60-min ischemia/reperfusion injury, while there was no change in female groups. Cognitive deficits were exacerbated in both male and female groups regardless of the injury period, while the sensorimotor dysfunction was worsened in male diabetic animals with longer ischemia time. These results suggest that diabetes negates the protection afforded by sex in young female animals, and post-stroke vascularization pattern is influenced by the degree of injury and correlates with functional outcome in both sexes. Vasculoprotection after acute ischemic stroke may provide a novel therapeutic strategy in diabetes." @default.
• W2890224840 created "2018-09-27" @default.
• W2890224840 creator A5006861070 @default.
• W2890224840 creator A5009087135 @default.
• W2890224840 creator A5034641228 @default.
• W2890224840 creator A5034973763 @default.
• W2890224840 creator A5043997159 @default.
• W2890224840 creator A5066738443 @default.
• W2890224840 creator A5072730832 @default.
• W2890224840 date "2019-01-01" @default.
• W2890224840 modified "2023-09-27" @default.
• W2890224840 title "Post-stroke neovascularization and functional outcomes differ in diabetes depending on severity of injury and sex: Potential link to hemorrhagic transformation" @default.
• W2890224840 cites W1537277145 @default.
• W2890224840 cites W1668720646 @default.
• W2890224840 cites W1900973864 @default.
• W2890224840 cites W1967456712 @default.
• W2890224840 cites W1988122391 @default.
• W2890224840 cites W1994270889 @default.
• W2890224840 cites W1999570560 @default.
• W2890224840 cites W2013133094 @default.
• W2890224840 cites W2026101044 @default.
• W2890224840 cites W2031186583 @default.
• W2890224840 cites W2042117724 @default.
• W2890224840 cites W2044443383 @default.
• W2890224840 cites W2047555160 @default.
• W2890224840 cites W2050749363 @default.
• W2890224840 cites W2051152021 @default.
• W2890224840 cites W2052687370 @default.
• W2890224840 cites W2063225783 @default.
• W2890224840 cites W2069195843 @default.
• W2890224840 cites W2070052932 @default.
• W2890224840 cites W2077867290 @default.
• W2890224840 cites W2081877609 @default.
• W2890224840 cites W2082482769 @default.
• W2890224840 cites W2082853248 @default.
• W2890224840 cites W2083900005 @default.
• W2890224840 cites W2088697955 @default.
• W2890224840 cites W2094838149 @default.
• W2890224840 cites W2104953152 @default.
• W2890224840 cites W2106322754 @default.
• W2890224840 cites W2110918252 @default.
• W2890224840 cites W2116415746 @default.
• W2890224840 cites W2120734151 @default.
• W2890224840 cites W2131556432 @default.
• W2890224840 cites W2143094951 @default.
• W2890224840 cites W2143167585 @default.
• W2890224840 cites W2152540044 @default.
• W2890224840 cites W2154823004 @default.
• W2890224840 cites W2155099072 @default.
• W2890224840 cites W2158732836 @default.
• W2890224840 cites W2166890974 @default.
• W2890224840 cites W2461625205 @default.
• W2890224840 cites W2463742113 @default.
• W2890224840 cites W2580792129 @default.
• W2890224840 cites W2591608778 @default.
• W2890224840 cites W2602609353 @default.
• W2890224840 cites W2737042056 @default.
• W2890224840 cites W2750828728 @default.
• W2890224840 cites W2759050422 @default.
• W2890224840 doi "https://doi.org/10.1016/j.expneurol.2018.09.013" @default.
• W2890224840 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6585988" @default.
• W2890224840 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30243988" @default.
• W2890224840 hasPublicationYear "2019" @default.
• W2890224840 type Work @default.
• W2890224840 sameAs 2890224840 @default.
• W2890224840 citedByCount "18" @default.
• W2890224840 countsByYear W28902248402019 @default.
• W2890224840 countsByYear W28902248402020 @default.
• W2890224840 countsByYear W28902248402021 @default.
• W2890224840 countsByYear W28902248402022 @default.
• W2890224840 countsByYear W28902248402023 @default.
• W2890224840 crossrefType "journal-article" @default.
• W2890224840 hasAuthorship W2890224840A5006861070 @default.
• W2890224840 hasAuthorship W2890224840A5009087135 @default.
• W2890224840 hasAuthorship W2890224840A5034641228 @default.
• W2890224840 hasAuthorship W2890224840A5034973763 @default.
• W2890224840 hasAuthorship W2890224840A5043997159 @default.
• W2890224840 hasAuthorship W2890224840A5066738443 @default.
• W2890224840 hasAuthorship W2890224840A5072730832 @default.
• W2890224840 hasBestOaLocation W28902248402 @default.
• W2890224840 hasConcept C105572291 @default.
• W2890224840 hasConcept C126322002 @default.
• W2890224840 hasConcept C127413603 @default.
• W2890224840 hasConcept C134018914 @default.
• W2890224840 hasConcept C141071460 @default.
• W2890224840 hasConcept C164705383 @default.
• W2890224840 hasConcept C2780645631 @default.
• W2890224840 hasConcept C541997718 @default.
• W2890224840 hasConcept C555293320 @default.
• W2890224840 hasConcept C71924100 @default.
• W2890224840 hasConcept C78519656 @default.
• W2890224840 hasConceptScore W2890224840C105572291 @default.
• W2890224840 hasConceptScore W2890224840C126322002 @default.
• W2890224840 hasConceptScore W2890224840C127413603 @default.
• W2890224840 hasConceptScore W2890224840C134018914 @default.
• W2890224840 hasConceptScore W2890224840C141071460 @default.
• W2890224840 hasConceptScore W2890224840C164705383 @default.
• W2890224840 hasConceptScore W2890224840C2780645631 @default.

• next