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- W2890241669 endingPage "284" @default.
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- W2890241669 abstract "Corticotropin-releasing factor (CRF) and the three homolog neuropeptides, urocortin (UCN) 1, 2 and 3, are the major neuroendocrine factors implicated in the response of the body to stress. Recent evidence suggests that UCNs have a significant role in the pathogenesis and management of cardiovascular disease, such as congestive heart failure, ischemic heart disease, and hypertension. These data led to the initiation of clinical trials testing a possible role of UCNs in the diagnosis and therapy of cardiovascular disease, with encouraging results. Here, we summarize the available literature concerning the role of UCNs in the cardiovascular system, focusing on the emerging data creating a potential for clinical applications." @default.
- W2890241669 created "2018-09-27" @default.
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- W2890241669 date "2019-01-01" @default.
- W2890241669 modified "2023-10-16" @default.
- W2890241669 title "Do urocortins have a role in treating cardiovascular disease?" @default.
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- W2890241669 doi "https://doi.org/10.1016/j.drudis.2018.09.004" @default.
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