Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890255498> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2890255498 endingPage "07003" @default.
- W2890255498 startingPage "07003" @default.
- W2890255498 abstract "Anemia is a common feature of chronic kidney disease (CKD). The current management of patients with anemia in CKD is controversial. These make anemia is one of the leading causes poor outcome in CKD patients. Our study focus to assess the effect of statin on hemoglobin level with an experimental model of CKD. We perform the animal model of CKD by subtotal nephrectomy procedure. A total of 20 male swiss was used in these study. All the animal divided into 4 groups: sham group (S), nephrectomy (Nx), simvastatin group 5 mg/kgBB (SV5), and simvastatin group 10 mg/kgBB (SV10). Hematological parameters (hemoglobin (Hb), white blood cells (WBC), red blood cell (RBC), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC)), and serum creatinine are measured at the end of the study. The hemoglobin levels in the Ux group decreased significantly compared with the S group (11.02 ± 0.46 vs 14.3 ± 0.15, p<0.0001). While in the SV group, statin administration led to an increase in hemoglobin levels compared with the Ux group but not statistically significant (SV5: 13.26±0.34; Sv10: 12.68±0.26). These results suggest that administration of statins in CKD may improve the condition of anemia by an unknown mechanism, while still requiring other treatment options to maximize the effect of therapy." @default.
- W2890255498 created "2018-09-27" @default.
- W2890255498 creator A5007781965 @default.
- W2890255498 creator A5011265391 @default.
- W2890255498 creator A5036651266 @default.
- W2890255498 creator A5040599193 @default.
- W2890255498 creator A5077342220 @default.
- W2890255498 date "2018-01-01" @default.
- W2890255498 modified "2023-10-01" @default.
- W2890255498 title "Statin and anemia in chronic kidney disease (CKD): an experimental study" @default.
- W2890255498 cites W1984393349 @default.
- W2890255498 cites W2027008805 @default.
- W2890255498 cites W2056096351 @default.
- W2890255498 cites W2078187198 @default.
- W2890255498 cites W2078542039 @default.
- W2890255498 cites W2098124630 @default.
- W2890255498 cites W2144113723 @default.
- W2890255498 cites W2174163447 @default.
- W2890255498 cites W2402533295 @default.
- W2890255498 cites W2572630720 @default.
- W2890255498 cites W2610617751 @default.
- W2890255498 doi "https://doi.org/10.1051/matecconf/201819707003" @default.
- W2890255498 hasPublicationYear "2018" @default.
- W2890255498 type Work @default.
- W2890255498 sameAs 2890255498 @default.
- W2890255498 citedByCount "2" @default.
- W2890255498 countsByYear W28902554982019 @default.
- W2890255498 countsByYear W28902554982020 @default.
- W2890255498 crossrefType "journal-article" @default.
- W2890255498 hasAuthorship W2890255498A5007781965 @default.
- W2890255498 hasAuthorship W2890255498A5011265391 @default.
- W2890255498 hasAuthorship W2890255498A5036651266 @default.
- W2890255498 hasAuthorship W2890255498A5040599193 @default.
- W2890255498 hasAuthorship W2890255498A5077342220 @default.
- W2890255498 hasBestOaLocation W28902554981 @default.
- W2890255498 hasConcept C126322002 @default.
- W2890255498 hasConcept C2775897519 @default.
- W2890255498 hasConcept C2776329913 @default.
- W2890255498 hasConcept C2778248108 @default.
- W2890255498 hasConcept C2778653478 @default.
- W2890255498 hasConcept C2778917026 @default.
- W2890255498 hasConcept C2780554921 @default.
- W2890255498 hasConcept C2780959883 @default.
- W2890255498 hasConcept C2781058662 @default.
- W2890255498 hasConcept C71924100 @default.
- W2890255498 hasConcept C90924648 @default.
- W2890255498 hasConceptScore W2890255498C126322002 @default.
- W2890255498 hasConceptScore W2890255498C2775897519 @default.
- W2890255498 hasConceptScore W2890255498C2776329913 @default.
- W2890255498 hasConceptScore W2890255498C2778248108 @default.
- W2890255498 hasConceptScore W2890255498C2778653478 @default.
- W2890255498 hasConceptScore W2890255498C2778917026 @default.
- W2890255498 hasConceptScore W2890255498C2780554921 @default.
- W2890255498 hasConceptScore W2890255498C2780959883 @default.
- W2890255498 hasConceptScore W2890255498C2781058662 @default.
- W2890255498 hasConceptScore W2890255498C71924100 @default.
- W2890255498 hasConceptScore W2890255498C90924648 @default.
- W2890255498 hasLocation W28902554981 @default.
- W2890255498 hasLocation W28902554982 @default.
- W2890255498 hasOpenAccess W2890255498 @default.
- W2890255498 hasPrimaryLocation W28902554981 @default.
- W2890255498 hasRelatedWork W1980882008 @default.
- W2890255498 hasRelatedWork W2014347187 @default.
- W2890255498 hasRelatedWork W2081284668 @default.
- W2890255498 hasRelatedWork W2262044591 @default.
- W2890255498 hasRelatedWork W2333538367 @default.
- W2890255498 hasRelatedWork W2566565925 @default.
- W2890255498 hasRelatedWork W2787736619 @default.
- W2890255498 hasRelatedWork W2805817862 @default.
- W2890255498 hasRelatedWork W3088836504 @default.
- W2890255498 hasRelatedWork W53496004 @default.
- W2890255498 hasVolume "197" @default.
- W2890255498 isParatext "false" @default.
- W2890255498 isRetracted "false" @default.
- W2890255498 magId "2890255498" @default.
- W2890255498 workType "article" @default.