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- W2890398825 abstract "The brewers' spent grain is a by-product generated during brewery process and is a potential source for arabinoxylans (AX) extraction. In the present work, the extraction and characterization of an arabinoxylan-rich fraction from brewers' spent grain (BSG-AX) were performed, and BSG-AX was evaluated as release matrix for caffeine. The BSG-AX showed an AX content of 72% (w/w), a ferulic acid content of 3.52 μg/mg BSG-AX, an Ara/Xyl ratio of 0.89, an intrinsic viscosity of 41.18 mL g−1, and a molecular weight of 43.80 kDa. The studied BSG-AX showed a good antioxidant capacity compared with other polysaccharide gums and was estimated by DPPH (114.41 μM Trolox equivalent/g BSG-AX) and FRAP (49.01 μmol Fe2+/g BSG-AX) assays. The partial specific volume (0.63 cm3 g−1), loss on drying (10.68%), swelling (10.87%), solubility (80.93%) and electrostatic interactions (by zeta potential, −3.44 to −9.17 mV) were determined and used to evaluate the application of the BSG-AX as release matrix. A film containing the BSG-AX, glycerol (as plasticizer) and caffeine (target drug) was prepared as release matrix. Glycerol promoted an increase in the extensibility and the surface smoothness of the BSG-AX-caffeine film. The drug was released (≈98%) in about 7 h. These results are promising to concern the design and use of BSG-AX based biofilms for the controlled release of bioactive compounds." @default.
- W2890398825 created "2018-09-27" @default.
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- W2890398825 date "2019-02-01" @default.
- W2890398825 modified "2023-10-16" @default.
- W2890398825 title "Physicochemical characterization of an arabinoxylan-rich fraction from brewers' spent grain and its application as a release matrix for caffeine" @default.
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- W2890398825 doi "https://doi.org/10.1016/j.foodres.2018.09.041" @default.
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