Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890493605> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2890493605 endingPage "S81" @default.
- W2890493605 startingPage "S81" @default.
- W2890493605 abstract "To study the association between global hemodynamics, blood gases, epileptiform EEG activity and survival after out-of-hospital CA (0HCA).We retrospectively analyzed 195 comatose post-CA patients. At least one EEG recording per patient was evaluated to diagnose epileptiform EEG activity. Refractory epileptiform EEG activity was defined as persisting epileptic activity on EEG despite the use of 2 or more anti-epileptics. The time weighted average mean arterial pressure 48 h (TWA-MAP48), the percentage of time with a MAP below 65 and above 85 mmHg and the percentage of time with normoxia, hypoxia (<70 mmHg), hyperoxia (>150 mmHg), normocapnia, hypocapnia (<35 mmHg) and hypercapnia (>45 mmHg) were calculated.We observed epileptiform EEG activity in 57 patients (29%). A shockable rhythm was associated with a decreased likelihood of epileptic activity on the EEG (OR: 0.41, 95%CI 0.22–0.79). We did not identify an association between the TWA-MAP48, the percentage of time with MAP below 65 mmHg or above 85 mmHg, blood gas variables and the risk of post-CA epileptiform EEG activity. The presence of epileptiform activity decreased the likelihood of survival independently (OR: 0.10, 95% CI: 0.04–0.24). Interestingly, survival rates of patients in whom the epileptiform EEG resolved (n = 20), were similar compared to patients without epileptiform activity on EEG (60% vs 67%,p = 0.617). Other independent predictors of survival were presence of basic life support (BLS) (OR:5.08, 95% CI 1.98–13.98), presence of a shockable rhythm (OR: 7.03, 95% CI: 3.18–16.55), average PaO2 (OR = 0.93, CI 95% 0.90–0.96) and% time MAP < 65 mmHg (OR: 0.96, CI 95% 0.94–0.98).Epileptiform EEG activity in post-CA patients is independently and inversely associated with survival and this effect is mainly driven by patients in whom this pattern is refractory over time despite treatment with anti-epileptic drugs. We did not identify an association between hemodynamic factors, blood gas variables and epileptiform EEG activity after CA, although both hypotension, hypoxia and epileptic EEG activity were predictors of survival." @default.
- W2890493605 created "2018-09-27" @default.
- W2890493605 creator A5000088389 @default.
- W2890493605 creator A5016773557 @default.
- W2890493605 creator A5031425704 @default.
- W2890493605 creator A5043264822 @default.
- W2890493605 creator A5057015603 @default.
- W2890493605 date "2018-10-01" @default.
- W2890493605 modified "2023-10-17" @default.
- W2890493605 title "Schmidtea mediterranea as an alternative model to predict carcinogenicity via its stem cell responses" @default.
- W2890493605 doi "https://doi.org/10.1016/j.toxlet.2018.06.550" @default.
- W2890493605 hasPublicationYear "2018" @default.
- W2890493605 type Work @default.
- W2890493605 sameAs 2890493605 @default.
- W2890493605 citedByCount "0" @default.
- W2890493605 crossrefType "journal-article" @default.
- W2890493605 hasAuthorship W2890493605A5000088389 @default.
- W2890493605 hasAuthorship W2890493605A5016773557 @default.
- W2890493605 hasAuthorship W2890493605A5031425704 @default.
- W2890493605 hasAuthorship W2890493605A5043264822 @default.
- W2890493605 hasAuthorship W2890493605A5057015603 @default.
- W2890493605 hasConcept C118552586 @default.
- W2890493605 hasConcept C126322002 @default.
- W2890493605 hasConcept C164705383 @default.
- W2890493605 hasConcept C17755696 @default.
- W2890493605 hasConcept C178790620 @default.
- W2890493605 hasConcept C185592680 @default.
- W2890493605 hasConcept C2777037550 @default.
- W2890493605 hasConcept C2778553927 @default.
- W2890493605 hasConcept C2778866228 @default.
- W2890493605 hasConcept C2781382112 @default.
- W2890493605 hasConcept C42219234 @default.
- W2890493605 hasConcept C522805319 @default.
- W2890493605 hasConcept C540031477 @default.
- W2890493605 hasConcept C71924100 @default.
- W2890493605 hasConcept C7836513 @default.
- W2890493605 hasConcept C84393581 @default.
- W2890493605 hasConceptScore W2890493605C118552586 @default.
- W2890493605 hasConceptScore W2890493605C126322002 @default.
- W2890493605 hasConceptScore W2890493605C164705383 @default.
- W2890493605 hasConceptScore W2890493605C17755696 @default.
- W2890493605 hasConceptScore W2890493605C178790620 @default.
- W2890493605 hasConceptScore W2890493605C185592680 @default.
- W2890493605 hasConceptScore W2890493605C2777037550 @default.
- W2890493605 hasConceptScore W2890493605C2778553927 @default.
- W2890493605 hasConceptScore W2890493605C2778866228 @default.
- W2890493605 hasConceptScore W2890493605C2781382112 @default.
- W2890493605 hasConceptScore W2890493605C42219234 @default.
- W2890493605 hasConceptScore W2890493605C522805319 @default.
- W2890493605 hasConceptScore W2890493605C540031477 @default.
- W2890493605 hasConceptScore W2890493605C71924100 @default.
- W2890493605 hasConceptScore W2890493605C7836513 @default.
- W2890493605 hasConceptScore W2890493605C84393581 @default.
- W2890493605 hasLocation W28904936051 @default.
- W2890493605 hasOpenAccess W2890493605 @default.
- W2890493605 hasPrimaryLocation W28904936051 @default.
- W2890493605 hasRelatedWork W2013489030 @default.
- W2890493605 hasRelatedWork W2023720628 @default.
- W2890493605 hasRelatedWork W2053674579 @default.
- W2890493605 hasRelatedWork W2078127741 @default.
- W2890493605 hasRelatedWork W2148634080 @default.
- W2890493605 hasRelatedWork W2187806848 @default.
- W2890493605 hasRelatedWork W2299826386 @default.
- W2890493605 hasRelatedWork W2418868523 @default.
- W2890493605 hasRelatedWork W2767633733 @default.
- W2890493605 hasRelatedWork W2802623680 @default.
- W2890493605 hasVolume "295" @default.
- W2890493605 isParatext "false" @default.
- W2890493605 isRetracted "false" @default.
- W2890493605 magId "2890493605" @default.
- W2890493605 workType "article" @default.