FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890500286> ?p ?o ?g. }

• W2890500286 abstract "To investigate the role of MAGE family member C2 in angiogenesis and epithelial-mesenchymal transition of non-small cell lung carcinoma.The Cancer Genome Atlas data set was analyzed to filter the highly expressed gene melanoma antigen family C2 in non-small cell lung carcinoma. Quantitative reverse transcription-polymerase chain reaction was performed to verify the overexpression of melanoma antigen family C2 in non-small cell lung carcinoma cell lines. Melanoma antigen family C2 complementary DNA and short hairpin RNA (shRNA) were transfected into SK-MES-1 cells to regulate melanoma antigen family C2 expression. Cell Counting Kit-8 assay, flow cytometry, wound healing assay, and Transwell assay were performed to investigate the effect of melanoma antigen family C2 on proliferation, apoptosis, migration, and invasion of SK-MES-1 cell line. Western blot was used to detect the expression of epithelial-mesenchymal transition markers. Enzyme-linked immunosorbent assay was performed to investigate the secretion of vascular endothelial growth factor, and tube formation assay was conducted to explore the effect of melanoma antigen family C2 on angiogenesis ability of the tumor. Tumor xenograft on nude mice and immunohistochemical/hematoxylin and eosin staining were also performed to detect the influence of melanoma antigen family C2 on growth and metastasis of non-small cell lung carcinoma cells.Melanoma antigen family C2 was highly expressed in non-small cell lung carcinoma cells; melanoma antigen family C2 promoted the expression of epithelial-mesenchymal transition-related proteins as well as enhance the secretion of vascular endothelial growth factor and promote angiogenesis; melanoma antigen family C2 promoted proliferation, migration, and invasion and suppressed apoptosis of non-small cell lung carcinoma cells. It could also facilitate growth and metastasis of non-small cell lung carcinoma in vivo.Melanoma antigen family C2 was a critical factor of angiogenesis and epithelial-mesenchymal transition in non-small cell lung carcinoma." @default.
• W2890500286 created "2018-09-27" @default.
• W2890500286 creator A5011283392 @default.
• W2890500286 creator A5018467739 @default.
• W2890500286 creator A5026372639 @default.
• W2890500286 creator A5034257827 @default.
• W2890500286 creator A5072603878 @default.
• W2890500286 creator A5078090771 @default.
• W2890500286 creator A5080360724 @default.
• W2890500286 date "2018-01-01" @default.
• W2890500286 modified "2023-10-16" @default.
• W2890500286 title "Study on Attenuating Angiogenesis and Epithelial–Mesenchymal Transition (EMT) of Non-Small Cell Lung Carcinoma (NSCLC) by RegulatingMAGEC2" @default.
• W2890500286 cites W1517718106 @default.
• W2890500286 cites W1964847767 @default.
• W2890500286 cites W1980350130 @default.
• W2890500286 cites W1981223981 @default.
• W2890500286 cites W1984802667 @default.
• W2890500286 cites W1985770572 @default.
• W2890500286 cites W1986246989 @default.
• W2890500286 cites W2023412257 @default.
• W2890500286 cites W2060118799 @default.
• W2890500286 cites W2065936889 @default.
• W2890500286 cites W2086856480 @default.
• W2890500286 cites W2117398240 @default.
• W2890500286 cites W2122169078 @default.
• W2890500286 cites W2129532336 @default.
• W2890500286 cites W2143926802 @default.
• W2890500286 cites W2152724801 @default.
• W2890500286 cites W2165905376 @default.
• W2890500286 cites W2168767893 @default.
• W2890500286 cites W2177862950 @default.
• W2890500286 cites W2214724576 @default.
• W2890500286 cites W2258823953 @default.
• W2890500286 cites W2275150503 @default.
• W2890500286 cites W2327474957 @default.
• W2890500286 cites W2331897708 @default.
• W2890500286 cites W2337568982 @default.
• W2890500286 cites W2408088858 @default.
• W2890500286 cites W2420947713 @default.
• W2890500286 cites W2534072499 @default.
• W2890500286 cites W2538191697 @default.
• W2890500286 cites W2551580107 @default.
• W2890500286 cites W2553967508 @default.
• W2890500286 cites W2589028259 @default.
• W2890500286 cites W854454069 @default.
• W2890500286 cites W1916312458 @default.
• W2890500286 doi "https://doi.org/10.1177/1533033818797587" @default.
• W2890500286 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6131299" @default.
• W2890500286 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30198403" @default.
• W2890500286 hasPublicationYear "2018" @default.
• W2890500286 type Work @default.
• W2890500286 sameAs 2890500286 @default.
• W2890500286 citedByCount "5" @default.
• W2890500286 countsByYear W28905002862019 @default.
• W2890500286 countsByYear W28905002862020 @default.
• W2890500286 countsByYear W28905002862022 @default.
• W2890500286 crossrefType "journal-article" @default.
• W2890500286 hasAuthorship W2890500286A5011283392 @default.
• W2890500286 hasAuthorship W2890500286A5018467739 @default.
• W2890500286 hasAuthorship W2890500286A5026372639 @default.
• W2890500286 hasAuthorship W2890500286A5034257827 @default.
• W2890500286 hasAuthorship W2890500286A5072603878 @default.
• W2890500286 hasAuthorship W2890500286A5078090771 @default.
• W2890500286 hasAuthorship W2890500286A5080360724 @default.
• W2890500286 hasBestOaLocation W28905002861 @default.
• W2890500286 hasConcept C121608353 @default.
• W2890500286 hasConcept C142724271 @default.
• W2890500286 hasConcept C167734588 @default.
• W2890500286 hasConcept C2777025900 @default.
• W2890500286 hasConcept C2777658100 @default.
• W2890500286 hasConcept C2779013556 @default.
• W2890500286 hasConcept C2780394083 @default.
• W2890500286 hasConcept C502942594 @default.
• W2890500286 hasConcept C54355233 @default.
• W2890500286 hasConcept C71924100 @default.
• W2890500286 hasConcept C76419328 @default.
• W2890500286 hasConcept C86803240 @default.
• W2890500286 hasConceptScore W2890500286C121608353 @default.
• W2890500286 hasConceptScore W2890500286C142724271 @default.
• W2890500286 hasConceptScore W2890500286C167734588 @default.
• W2890500286 hasConceptScore W2890500286C2777025900 @default.
• W2890500286 hasConceptScore W2890500286C2777658100 @default.
• W2890500286 hasConceptScore W2890500286C2779013556 @default.
• W2890500286 hasConceptScore W2890500286C2780394083 @default.
• W2890500286 hasConceptScore W2890500286C502942594 @default.
• W2890500286 hasConceptScore W2890500286C54355233 @default.
• W2890500286 hasConceptScore W2890500286C71924100 @default.
• W2890500286 hasConceptScore W2890500286C76419328 @default.
• W2890500286 hasConceptScore W2890500286C86803240 @default.
• W2890500286 hasLocation W28905002861 @default.
• W2890500286 hasLocation W28905002862 @default.
• W2890500286 hasLocation W28905002863 @default.
• W2890500286 hasLocation W28905002864 @default.
• W2890500286 hasOpenAccess W2890500286 @default.
• W2890500286 hasPrimaryLocation W28905002861 @default.
• W2890500286 hasRelatedWork W1576290062 @default.
• W2890500286 hasRelatedWork W1780842662 @default.
• W2890500286 hasRelatedWork W2150529368 @default.
• W2890500286 hasRelatedWork W2413189820 @default.
• W2890500286 hasRelatedWork W2623003466 @default.

• next