Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890504211> ?p ?o ?g. }
- W2890504211 endingPage "1987" @default.
- W2890504211 startingPage "1980" @default.
- W2890504211 abstract "Background Current guidelines suggest treatment for many individuals who may never develop a stroke. We hypothesized that a combination of coronary artery calcification (CAC) and carotid artery intima-media thickness (C IMT) data could better individualize risk assessment for ischemic stroke and transient ischemic attack events. Methods A total of 4720 individuals from the Multi-Ethnic Study of Atherosclerosis were evaluated for ischemic stroke and transient ischemic attack. Cox proportional hazards models for time to incident ischemic stroke/transient ischemic attack were used to examine CAC and CIMT as ischemic stroke/transient ischemic attack predictors in addition to traditional risk factors. We calculated the 10-year number needed to treat by applying the benefit observed in ASCOT-LLA to the observed event rates within CAC and CIMT strata. Results Median follow-up was 13.1 years. Compared with individuals with no CAC and with CIMT ≤ 75th percentile, stroke/transient ischemic attack risk increased progressively with each CAC category (0, 1–100, >100) among individuals with CIMT > 75th percentile. Among participants eligible for statin therapy based on the 2013 atherosclerotic cardiovascular disease (ASCVD) guidelines (ASCVD risk of >5%), 739/2906 (25%) had no CAC and CIMT ≤ 75th percentile and an observed ischemic stroke/transient ischemic attack rate of 2.49 per 1000 person-years. The predicted 10-year number needed to treat was 292 for no CAC and CIMT ≤ 75th percentile and 57 for CAC > 100 and CIMT > 75th percentile. Conclusion The combination of CIMT and CAC could serve to further refine risk calculation for ischemic stroke/transient ischemic attack prevention and may prioritize those in most need of statin therapy to reduce ischemic stroke/transient ischemic attack risk." @default.
- W2890504211 created "2018-09-27" @default.
- W2890504211 creator A5007236534 @default.
- W2890504211 creator A5008531984 @default.
- W2890504211 creator A5012676647 @default.
- W2890504211 creator A5016216017 @default.
- W2890504211 creator A5022452269 @default.
- W2890504211 creator A5037988990 @default.
- W2890504211 creator A5055013057 @default.
- W2890504211 creator A5062424225 @default.
- W2890504211 creator A5065686655 @default.
- W2890504211 creator A5068597016 @default.
- W2890504211 creator A5079665496 @default.
- W2890504211 creator A5080567374 @default.
- W2890504211 date "2018-09-05" @default.
- W2890504211 modified "2023-09-23" @default.
- W2890504211 title "Coronary artery calcium and carotid artery intima-media thickness for the prediction of stroke and benefit from statins" @default.
- W2890504211 cites W1252141492 @default.
- W2890504211 cites W1821026158 @default.
- W2890504211 cites W1904745228 @default.
- W2890504211 cites W1966893587 @default.
- W2890504211 cites W2011293611 @default.
- W2890504211 cites W2015185375 @default.
- W2890504211 cites W2031185570 @default.
- W2890504211 cites W2102320098 @default.
- W2890504211 cites W2102613400 @default.
- W2890504211 cites W2107175684 @default.
- W2890504211 cites W2114635452 @default.
- W2890504211 cites W2127427378 @default.
- W2890504211 cites W2144716937 @default.
- W2890504211 cites W2156097706 @default.
- W2890504211 cites W2167830562 @default.
- W2890504211 cites W2168536722 @default.
- W2890504211 cites W2292719256 @default.
- W2890504211 cites W2306713465 @default.
- W2890504211 cites W2316167515 @default.
- W2890504211 cites W2402599050 @default.
- W2890504211 cites W2522171479 @default.
- W2890504211 cites W2576755698 @default.
- W2890504211 cites W2589085246 @default.
- W2890504211 cites W2735021150 @default.
- W2890504211 cites W2801019686 @default.
- W2890504211 cites W2801486783 @default.
- W2890504211 cites W4236673002 @default.
- W2890504211 cites W4292550095 @default.
- W2890504211 cites W75920495 @default.
- W2890504211 cites W924133762 @default.
- W2890504211 doi "https://doi.org/10.1177/2047487318798058" @default.
- W2890504211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30183342" @default.
- W2890504211 hasPublicationYear "2018" @default.
- W2890504211 type Work @default.
- W2890504211 sameAs 2890504211 @default.
- W2890504211 citedByCount "16" @default.
- W2890504211 countsByYear W28905042112019 @default.
- W2890504211 countsByYear W28905042112020 @default.
- W2890504211 countsByYear W28905042112021 @default.
- W2890504211 countsByYear W28905042112022 @default.
- W2890504211 crossrefType "journal-article" @default.
- W2890504211 hasAuthorship W2890504211A5007236534 @default.
- W2890504211 hasAuthorship W2890504211A5008531984 @default.
- W2890504211 hasAuthorship W2890504211A5012676647 @default.
- W2890504211 hasAuthorship W2890504211A5016216017 @default.
- W2890504211 hasAuthorship W2890504211A5022452269 @default.
- W2890504211 hasAuthorship W2890504211A5037988990 @default.
- W2890504211 hasAuthorship W2890504211A5055013057 @default.
- W2890504211 hasAuthorship W2890504211A5062424225 @default.
- W2890504211 hasAuthorship W2890504211A5065686655 @default.
- W2890504211 hasAuthorship W2890504211A5068597016 @default.
- W2890504211 hasAuthorship W2890504211A5079665496 @default.
- W2890504211 hasAuthorship W2890504211A5080567374 @default.
- W2890504211 hasBestOaLocation W28905042112 @default.
- W2890504211 hasConcept C105795698 @default.
- W2890504211 hasConcept C122048520 @default.
- W2890504211 hasConcept C126322002 @default.
- W2890504211 hasConcept C127413603 @default.
- W2890504211 hasConcept C164705383 @default.
- W2890504211 hasConcept C2776839432 @default.
- W2890504211 hasConcept C2778213512 @default.
- W2890504211 hasConcept C2779339615 @default.
- W2890504211 hasConcept C2780645631 @default.
- W2890504211 hasConcept C2987047532 @default.
- W2890504211 hasConcept C2994533308 @default.
- W2890504211 hasConcept C3020199598 @default.
- W2890504211 hasConcept C33923547 @default.
- W2890504211 hasConcept C50382708 @default.
- W2890504211 hasConcept C541997718 @default.
- W2890504211 hasConcept C71924100 @default.
- W2890504211 hasConcept C78519656 @default.
- W2890504211 hasConceptScore W2890504211C105795698 @default.
- W2890504211 hasConceptScore W2890504211C122048520 @default.
- W2890504211 hasConceptScore W2890504211C126322002 @default.
- W2890504211 hasConceptScore W2890504211C127413603 @default.
- W2890504211 hasConceptScore W2890504211C164705383 @default.
- W2890504211 hasConceptScore W2890504211C2776839432 @default.
- W2890504211 hasConceptScore W2890504211C2778213512 @default.
- W2890504211 hasConceptScore W2890504211C2779339615 @default.
- W2890504211 hasConceptScore W2890504211C2780645631 @default.
- W2890504211 hasConceptScore W2890504211C2987047532 @default.