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• W2890517411 abstract "Herein, we describe the use of gamma irradiation to prepare hydrogels comprising α-cellulose and cellulose nanocrystal (CNC)-reinforced gelatin in the absence of crosslinking agents. In this study, cellulose was extracted from rice husks by an alkali and bleaching treatment followed by acid hydrolysis to produce CNC. A semi-interpenetrating network (semi-IPN) of hydrogels was developed by the miscibility between gelatin and cellulosic materials. Compared to those prepared from α-cellulose, hydrogels prepared by dispersion of CNCs exhibited remarkably enhanced stiffness and swelling properties, which was ascribed to the uniform distribution of CNCs and their increased crystallinity. Improved pore structure, arrangement, and rigidity of CNC-reinforced gelatin hydrogels, which induced the swelling mechanism resulting in higher and faster water uptake was observed with a scanning electron microscope (SEM), compared to cellulose-reinforced gelatin hydrogels. Moreover, in vitro drug profiling demonstrated that CNC/gelatin hydrogels exhibit good drug loading/release behavior and are thus suitable for use in drug-delivery applications." @default.
• W2890517411 created "2018-09-27" @default.
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• W2890517411 date "2018-09-21" @default.
• W2890517411 modified "2023-10-14" @default.
• W2890517411 title "Gamma Irradiation-Assisted Synthesis of Cellulose Nanocrystal-Reinforced Gelatin Hydrogels" @default.
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• W2890517411 doi "https://doi.org/10.3390/nano8100749" @default.
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