FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890553545> ?p ?o ?g. }

• W2890553545 endingPage "598" @default.
• W2890553545 startingPage "593" @default.
• W2890553545 abstract "Background: Recent evidence indicates that the PVT1, CCDC26, and CCAT1 long noncoding RNAs (lncRNAs) are involved in the leukemogenic process. This study quantified the expression levels of the PVT1, CCDC26, and CCAT1 lncRNAs in patients with acute myeloid leukemia (AML) and also correlated their expression levels with the clinicopathological features of the patients. Materials and Methods: The expression levels of the PVT1, CCDC26, and CCAT1 lncRNAs were analyzed using quantitative reverse transcription–polymerase chain reaction of bone marrow specimens obtained from 86 AML patients, 48 AML-M3 patients, and 40 normal controls. Results: No differences were found between the combined AML patient populations and the healthy controls with respect to the expression levels of PVT1, CCDC26, and CCAT1 (p = 0.35, p = 0.09, and p = 0.77, respectively). However, compared with the controls, the AML-M3 patients had higher PVT1 expression (p = 0.017). Furthermore, high-risk AML-M3 patients manifested higher expression levels of PVT1 than low- and intermediate-risk groups. In addition, distinctive CCDC26 and CCAT1 expression levels were observed among patients with different French–American–British subtypes (p = 0.001 for CCDC26 and p = 0.013 for CCAT1). Compared with the healthy controls, AML-M4 and M5 had higher CCAT1 expression (p = 0.04) and AML-M2 and AML-M4/M5 patients had higher CCDC26 expression (p < 0.001 and p = 0.02, respectively). In addition, different patterns of CCDC26 expression were found among the different cytogenetic risk subtypes (p = 0.005). Finally, patients with intermediate cytogenetic risk showed higher CCDC26 expression levels. Conclusion: The differential expression of the PVT1, CCDC26, and CCAT1 lncRNAs in different AML subtypes suggests that the deregulation of these transcripts may function in the multistep leukemogenic process and that they may serve as new therapeutic targets for this malignancy." @default.
• W2890553545 created "2018-09-27" @default.
• W2890553545 creator A5013196988 @default.
• W2890553545 creator A5017552039 @default.
• W2890553545 creator A5040348288 @default.
• W2890553545 creator A5041416172 @default.
• W2890553545 creator A5059798775 @default.
• W2890553545 creator A5064053791 @default.
• W2890553545 creator A5064071536 @default.
• W2890553545 creator A5066883249 @default.
• W2890553545 creator A5075077705 @default.
• W2890553545 creator A5082104404 @default.
• W2890553545 creator A5086980259 @default.
• W2890553545 creator A5090828119 @default.
• W2890553545 date "2018-10-01" @default.
• W2890553545 modified "2023-09-26" @default.
• W2890553545 title "Expression Analysis of <i>PVT1</i>, <i>CCDC26,</i> and <i>CCAT1</i> Long Noncoding RNAs in Acute Myeloid Leukemia Patients" @default.
• W2890553545 cites W1977572305 @default.
• W2890553545 cites W2030881808 @default.
• W2890553545 cites W2079588819 @default.
• W2890553545 cites W2107398329 @default.
• W2890553545 cites W2111250953 @default.
• W2890553545 cites W2115111607 @default.
• W2890553545 cites W2134913339 @default.
• W2890553545 cites W2136309995 @default.
• W2890553545 cites W2150113701 @default.
• W2890553545 cites W2157138741 @default.
• W2890553545 cites W2162098634 @default.
• W2890553545 cites W2165725865 @default.
• W2890553545 cites W2166810745 @default.
• W2890553545 cites W2335029242 @default.
• W2890553545 cites W2346543048 @default.
• W2890553545 cites W2488759133 @default.
• W2890553545 cites W2560901357 @default.
• W2890553545 cites W2587631365 @default.
• W2890553545 cites W2595120264 @default.
• W2890553545 cites W2615184377 @default.
• W2890553545 cites W2746321064 @default.
• W2890553545 cites W2773858712 @default.
• W2890553545 cites W2791949310 @default.
• W2890553545 cites W2796730950 @default.
• W2890553545 doi "https://doi.org/10.1089/gtmb.2018.0143" @default.
• W2890553545 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30222365" @default.
• W2890553545 hasPublicationYear "2018" @default.
• W2890553545 type Work @default.
• W2890553545 sameAs 2890553545 @default.
• W2890553545 citedByCount "27" @default.
• W2890553545 countsByYear W28905535452019 @default.
• W2890553545 countsByYear W28905535452020 @default.
• W2890553545 countsByYear W28905535452021 @default.
• W2890553545 countsByYear W28905535452022 @default.
• W2890553545 countsByYear W28905535452023 @default.
• W2890553545 crossrefType "journal-article" @default.
• W2890553545 hasAuthorship W2890553545A5013196988 @default.
• W2890553545 hasAuthorship W2890553545A5017552039 @default.
• W2890553545 hasAuthorship W2890553545A5040348288 @default.
• W2890553545 hasAuthorship W2890553545A5041416172 @default.
• W2890553545 hasAuthorship W2890553545A5059798775 @default.
• W2890553545 hasAuthorship W2890553545A5064053791 @default.
• W2890553545 hasAuthorship W2890553545A5064071536 @default.
• W2890553545 hasAuthorship W2890553545A5066883249 @default.
• W2890553545 hasAuthorship W2890553545A5075077705 @default.
• W2890553545 hasAuthorship W2890553545A5082104404 @default.
• W2890553545 hasAuthorship W2890553545A5086980259 @default.
• W2890553545 hasAuthorship W2890553545A5090828119 @default.
• W2890553545 hasConcept C104317684 @default.
• W2890553545 hasConcept C126322002 @default.
• W2890553545 hasConcept C143998085 @default.
• W2890553545 hasConcept C2777394393 @default.
• W2890553545 hasConcept C2778461978 @default.
• W2890553545 hasConcept C2778729363 @default.
• W2890553545 hasConcept C2779282312 @default.
• W2890553545 hasConcept C49105822 @default.
• W2890553545 hasConcept C502942594 @default.
• W2890553545 hasConcept C54355233 @default.
• W2890553545 hasConcept C62203573 @default.
• W2890553545 hasConcept C67705224 @default.
• W2890553545 hasConcept C71924100 @default.
• W2890553545 hasConcept C86803240 @default.
• W2890553545 hasConcept C90924648 @default.
• W2890553545 hasConceptScore W2890553545C104317684 @default.
• W2890553545 hasConceptScore W2890553545C126322002 @default.
• W2890553545 hasConceptScore W2890553545C143998085 @default.
• W2890553545 hasConceptScore W2890553545C2777394393 @default.
• W2890553545 hasConceptScore W2890553545C2778461978 @default.
• W2890553545 hasConceptScore W2890553545C2778729363 @default.
• W2890553545 hasConceptScore W2890553545C2779282312 @default.
• W2890553545 hasConceptScore W2890553545C49105822 @default.
• W2890553545 hasConceptScore W2890553545C502942594 @default.
• W2890553545 hasConceptScore W2890553545C54355233 @default.
• W2890553545 hasConceptScore W2890553545C62203573 @default.
• W2890553545 hasConceptScore W2890553545C67705224 @default.
• W2890553545 hasConceptScore W2890553545C71924100 @default.
• W2890553545 hasConceptScore W2890553545C86803240 @default.
• W2890553545 hasConceptScore W2890553545C90924648 @default.
• W2890553545 hasIssue "10" @default.
• W2890553545 hasLocation W28905535451 @default.
• W2890553545 hasLocation W28905535452 @default.

• next