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- W2890561822 abstract "The frequency of adenomyosis in pregnancy has been increasing in recent years, along with the increase in the number of pregnancies in women of advanced age and the increase in pregnancies achieved by fertility treatments.Adenomyosis has been reported to be associated with poor pregnancy outcomes, including an increased risk of preterm delivery, preterm premature rupture of membranes, and fetal growth restriction.However, the potential impact of adenomyosis on the outcomes of pregnancy is still unclear, because few studies have addressed the associations between adenomyosis and pregnancy outcomes, and because the study populations of those studies were small. In addition, no data are available for analyzing the relationship between the type of adenomyosis (focal or diffuse) and the outcomes of pregnancy. To investigate the impact of adenomyosis on the complications and outcomes of pregnancy in Japan, a multicenter retrospective survey of pregnant patients with adenomyosis was carried out. A multicenter retrospective survey. We carried out a nationwide survey to evaluate the involvement of adenomyosis in pregnancy outcomes as an official project of the Japan Society of Obstetrics and Gynecology. A questionnaire was sent to 725 Japanese medical facilities and the retrospective analysis was based on the clinical records of each facility. The questionnaire inquired information related to adenomyosis, including the methods by which it was diagnosed, size (major axis), type (focal or diffuse), localization (anterior wall or posterior wall), pretreatment before pregnancy (medication, conservative operation, no pretreatment), and pregnancy complications. Data were obtained on the cases of 272 pregnant women with adenomyosis from 65 facilities. The complications of pregnancy included miscarriage before 12 weeks of pregnancy (14.8%), miscarriage after 12 weeks of pregnancy (9.9%), pre-term delivery (24.4%), fetal growth restriction (11.8%), pregnancy-induced hypertension (9.9%), intrauterine infection (7.3%), and cervical incompetency (5.3%). The rates of pregnancy complications in the three groups classified according to pretreatment for adenomyosis (no pretreatment, medication, surgery) did not differ to a statistically significant extent. The rates of miscarriage (>12 weeks) and cervical incompetency increased according to the size of the adenomyosis. The rates of pregnancy-induced hypertension and uterine infection in patients with diffuse-type adenomyosis were higher than that in patients with focal-type adenomyosis. Our results show that the increased size and diffuse type of adenomyosis are associated with adverse pregnancy outcome. We should be aware of the higher incidence of pregnancy-induced hypertension and uterine infection in patients with diffuse-type adenomyosis." @default.
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- W2890561822 date "2018-09-01" @default.
- W2890561822 modified "2023-09-30" @default.
- W2890561822 title "Complications and outcomes of pregnant women with adenomyosis in Japan" @default.
- W2890561822 doi "https://doi.org/10.1016/j.fertnstert.2018.07.1088" @default.
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