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• W2890564162 abstract "Here we describe FitHiChIP (github.com/ay-lab/FitHiChIP), a computational method for identifying chromatin contacts among regulatory regions such as en-hancers and promoters from HiChIP/PLAC-seq data. FitHiChIP jointly models the non-uniform coverage and genomic distance scaling of HiChIP data, captures previously validated enhancer interactions for several genes including MYC and TP53, and recovers contacts genome-wide that are supported by ChIA-PET, pro-moter capture Hi-C and Hi-C data. FitHiChIP also provides a framework for differential contact analysis as showcased in a comparison of HiChIP data we have generated for two distinct immune cell types." @default.
• W2890564162 created "2018-09-27" @default.
• W2890564162 creator A5012587144 @default.
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• W2890564162 date "2019-07-08" @default.
• W2890564162 modified "2023-09-22" @default.
• W2890564162 title "FitHiChIP: Identification of significant chromatin contacts from HiChIP data" @default.
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• W2890564162 doi "https://doi.org/10.5281/zenodo.3255048" @default.
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