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- W2890591485 abstract "Cartilaginous differentiation/chondroid metaplasia in the peritoneum is extremely rare. The majority of patients with cartilaginous differentiation/chondroid metaplasia had a clinical history of prior abdominal surgery. We report an extremely rare case of cartilaginous differentiation/chondroid metaplasia in the peritoneum in a 72-year-old man with a medical history of hepatitis C viral infection, hypertension, and bilateral choreiform movements but no abdominal surgical history. The patient presented to the emergency department with painless jaundice, diarrhea, weight loss, nausea, and decreased appetite. Computer tomography of the abdomen revealed moderate to severe intrahepatic and extrahepatic biliary duct dilatation with a moderately distended gallbladder. Endoscopic ultrasound examination showed a 2.1-cm pancreatic head mass obstructing the bile and pancreatic ducts. A fine-needle aspiration cytology was positive for adenocarcinoma. At surgery, the patient was found to have a nonresectable pancreatic head tumor with possible invasion into the superior mesenteric vein (SMV) and previously undiagnosed hepatic cirrhosis. A single firm, pale tan-white nodule measuring 3 mm in the greatest dimension was incidentally found on the peritoneal surface at the porta hepatis. Microscopic examination of the peritoneal nodule showed a well-circumscribed mature hyaline cartilage with no cytological atypia. Only hepaticojejunostomy and cholecystectomy were performed because of the presence of possible invasion into the SMV and liver cirrhosis. The possible histogenesis of cartilaginous differentiation/chondroid metaplasia in the peritoneum includes a possible differentiation of submesothelial multipotent stem cell into a cartilaginous tissue in reaction to prior abdominal trauma or surgery. The present case is intriguing in that the patient has no history of abdominal trauma or surgery." @default.
- W2890591485 created "2018-09-27" @default.
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- W2890591485 date "2018-09-21" @default.
- W2890591485 modified "2023-09-26" @default.
- W2890591485 title "Cartilaginous Differentiation/Chondroid Metaplasia in the Peritoneum Not Associated With Prior Surgery: A Case Report and Review of the Literature" @default.
- W2890591485 doi "https://doi.org/10.1093/ajcp/aqy090.106" @default.
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