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- W289063586 abstract "There is much evidence that neuropeptide substance P is involved in neurogenic inflammation and is an important neurotransmitter and neurmodulator compound. In addition, substance P plays an important role in inflammation and immunity. Macrophages can be activated by substance P which provokes the release of inflammatory compounds such as interleukins, chemokines and growth factors. Substance P is involved in the mechanism of pain through the trigeminal nerve which runs through the head, temporal and sinus cavity. Substance P also activates mast cells to release inflammatory mediators such as arachindonic acid compound, cytokines/chemokines and histamine. The release of these chemical mediators is crucial for inflammatory response. Among these mediators there are prostoglandins and leukotrines. Here we review the impact of substance P on inflammatory compounds." @default.
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- W289063586 date "2012-10-01" @default.
- W289063586 modified "2023-10-02" @default.
- W289063586 title "Impact and Neuropeptide Substance Pan Inflammatory Compound on Arachidonic Acid Compound Generation" @default.
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- W289063586 doi "https://doi.org/10.1177/039463201202500403" @default.
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