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- W2890639107 abstract "Accurate transcription is required for the faithful expression of genetic information. Surprisingly though, little is known about the mechanisms that control the fidelity of transcription. To fill this gap in scientific knowledge, we recently optimized the circle-sequencing assay to detect transcription errors throughout the transcriptome of Saccharomyces cerevisiae, Drosophila melanogaster, and Caenorhabditis elegans. This protocol will provide researchers with a powerful new tool to map the landscape of transcription errors in eukaryotic cells so that the mechanisms that control the fidelity of transcription can be elucidated in unprecedented detail." @default.
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- W2890639107 date "2018-09-13" @default.
- W2890639107 modified "2023-10-14" @default.
- W2890639107 title "Genome-wide Surveillance of Transcription Errors in Eukaryotic Organisms" @default.
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- W2890639107 doi "https://doi.org/10.3791/57731" @default.
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