FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890653325> ?p ?o ?g. }

• W2890653325 endingPage "698" @default.
• W2890653325 startingPage "692" @default.
• W2890653325 abstract "Peripheral airway impairment, although frequently unrecognized, is a risk factor for poor asthma control, loss of control, increased exacerbations, airway hyperresponsiveness, and loss of lung function with age, even in patients with well-controlled asthma.To determine the presence of peripheral airway impairment by impulse oscillometry and forced expiratory flow between 25% and 75% (FEF25%-75%) in children whose asthma is well controlled by National Asthma Education and Prevention Program (NAEPP) guidelines.In this retrospective, cross-sectional analysis, outcomes were evaluated across 192 encounters in 139 patients with moderate to severe asthma, ages 4-18 years. Receiver operator characteristic curves were created and oscillometry thresholds determined by maximizing the sum of sensitivity and specificity to identify those whose condition is not well controlled. Impairment was then identified for those whose condition was well controlled when these age-dependent oscillometry thresholds were met for each IOS measure or FEF25%-75% < 65% of predicted.Reactance at 5 Hz (X5) appeared most robust to identify peripheral airway impairment. In 96 well-controlled asthma encounters, impairment was identified by X5 in approximately 20% and 45% for those younger than 12 years and adolescents, respectively, compared with a maximum of 10% with FEF25%-75% in the adolescent cohort (P < .05).We conclude that peripheral airway impairment, determined by oscillometry, is common in patients with well-controlled asthma across age cohorts. X5 with optimal cut points ≤ -3.8, ≤ -2.5, and ≤ -1.5 cmH2O/L/s for ages 4-7, 8-11, and >12 years, provides the clinician with a practical tool to identify the presence of the peripheral airway impairment phenotype that is consistently superior to FEF25%-75%. This recognition, if confirmed, may reduce the risk of asthma-associated consequences with earlier and more targeted therapy." @default.
• W2890653325 created "2018-09-27" @default.
• W2890653325 creator A5000133165 @default.
• W2890653325 creator A5013950909 @default.
• W2890653325 creator A5040799896 @default.
• W2890653325 creator A5047439185 @default.
• W2890653325 creator A5049604896 @default.
• W2890653325 creator A5055115529 @default.
• W2890653325 creator A5087553931 @default.
• W2890653325 date "2018-12-01" @default.
• W2890653325 modified "2023-10-01" @default.
• W2890653325 title "Recognition of the peripheral airway impairment phenotype in children with well-controlled asthma" @default.
• W2890653325 cites W1624971058 @default.
• W2890653325 cites W1809148818 @default.
• W2890653325 cites W1968078805 @default.
• W2890653325 cites W1972881815 @default.
• W2890653325 cites W2003852436 @default.
• W2890653325 cites W2015990891 @default.
• W2890653325 cites W2033091014 @default.
• W2890653325 cites W2037832985 @default.
• W2890653325 cites W2047761854 @default.
• W2890653325 cites W2077126291 @default.
• W2890653325 cites W2080725789 @default.
• W2890653325 cites W2081344110 @default.
• W2890653325 cites W2108499927 @default.
• W2890653325 cites W2112468123 @default.
• W2890653325 cites W2114619672 @default.
• W2890653325 cites W2116822763 @default.
• W2890653325 cites W2125712363 @default.
• W2890653325 cites W2134773545 @default.
• W2890653325 cites W2139460874 @default.
• W2890653325 cites W2141343329 @default.
• W2890653325 cites W2144427117 @default.
• W2890653325 cites W2167229428 @default.
• W2890653325 cites W2168295076 @default.
• W2890653325 cites W2190661052 @default.
• W2890653325 cites W2214050053 @default.
• W2890653325 cites W2226938759 @default.
• W2890653325 cites W2239683572 @default.
• W2890653325 cites W2319554819 @default.
• W2890653325 cites W2345786061 @default.
• W2890653325 cites W2601675613 @default.
• W2890653325 cites W2621308914 @default.
• W2890653325 cites W2758069030 @default.
• W2890653325 doi "https://doi.org/10.1016/j.anai.2018.08.023" @default.
• W2890653325 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30194972" @default.
• W2890653325 hasPublicationYear "2018" @default.
• W2890653325 type Work @default.
• W2890653325 sameAs 2890653325 @default.
• W2890653325 citedByCount "22" @default.
• W2890653325 countsByYear W28906533252019 @default.
• W2890653325 countsByYear W28906533252020 @default.
• W2890653325 countsByYear W28906533252021 @default.
• W2890653325 countsByYear W28906533252022 @default.
• W2890653325 countsByYear W28906533252023 @default.
• W2890653325 crossrefType "journal-article" @default.
• W2890653325 hasAuthorship W2890653325A5000133165 @default.
• W2890653325 hasAuthorship W2890653325A5013950909 @default.
• W2890653325 hasAuthorship W2890653325A5040799896 @default.
• W2890653325 hasAuthorship W2890653325A5047439185 @default.
• W2890653325 hasAuthorship W2890653325A5049604896 @default.
• W2890653325 hasAuthorship W2890653325A5055115529 @default.
• W2890653325 hasAuthorship W2890653325A5087553931 @default.
• W2890653325 hasConcept C105922876 @default.
• W2890653325 hasConcept C126322002 @default.
• W2890653325 hasConcept C164705383 @default.
• W2890653325 hasConcept C187212893 @default.
• W2890653325 hasConcept C2776042228 @default.
• W2890653325 hasConcept C42219234 @default.
• W2890653325 hasConcept C46762472 @default.
• W2890653325 hasConcept C71924100 @default.
• W2890653325 hasConcept C72563966 @default.
• W2890653325 hasConceptScore W2890653325C105922876 @default.
• W2890653325 hasConceptScore W2890653325C126322002 @default.
• W2890653325 hasConceptScore W2890653325C164705383 @default.
• W2890653325 hasConceptScore W2890653325C187212893 @default.
• W2890653325 hasConceptScore W2890653325C2776042228 @default.
• W2890653325 hasConceptScore W2890653325C42219234 @default.
• W2890653325 hasConceptScore W2890653325C46762472 @default.
• W2890653325 hasConceptScore W2890653325C71924100 @default.
• W2890653325 hasConceptScore W2890653325C72563966 @default.
• W2890653325 hasIssue "6" @default.
• W2890653325 hasLocation W28906533251 @default.
• W2890653325 hasLocation W28906533252 @default.
• W2890653325 hasOpenAccess W2890653325 @default.
• W2890653325 hasPrimaryLocation W28906533251 @default.
• W2890653325 hasRelatedWork W1908814627 @default.
• W2890653325 hasRelatedWork W2012405193 @default.
• W2890653325 hasRelatedWork W2086267853 @default.
• W2890653325 hasRelatedWork W2212663251 @default.
• W2890653325 hasRelatedWork W2405998678 @default.
• W2890653325 hasRelatedWork W2415654257 @default.
• W2890653325 hasRelatedWork W2603773853 @default.
• W2890653325 hasRelatedWork W2778613212 @default.
• W2890653325 hasRelatedWork W3141700921 @default.
• W2890653325 hasRelatedWork W4235375593 @default.
• W2890653325 hasVolume "121" @default.
• W2890653325 isParatext "false" @default.

• next