Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890655424> ?p ?o ?g. }
- W2890655424 abstract "The factors that govern assembly of the gut microbiota are insufficiently understood. Here, we test the hypothesis that inter-individual microbiota variation can arise solely from differences in the order and timing by which the gut is colonized early in life. Experiments in which mice were inoculated in sequence either with two complex seed communities or a cocktail of four bacterial strains and a seed community revealed that colonization order influenced both the outcome of community assembly and the ecological success of individual colonizers. Historical contingency and priority effects also occurred in Rag1-/- mice, suggesting that the adaptive immune system is not a major contributor to these processes. In conclusion, this study established a measurable effect of colonization history on gut microbiota assembly in a model in which host and environmental factors were strictly controlled, illuminating a potential cause for the high levels of unexplained individuality in host-associated microbial communities." @default.
- W2890655424 created "2018-09-27" @default.
- W2890655424 creator A5001473679 @default.
- W2890655424 creator A5002256118 @default.
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- W2890655424 creator A5083449552 @default.
- W2890655424 creator A5088569687 @default.
- W2890655424 date "2018-09-18" @default.
- W2890655424 modified "2023-10-06" @default.
- W2890655424 title "Experimental evaluation of the importance of colonization history in early-life gut microbiota assembly" @default.
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