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- W2890665250 abstract "Despite timely intervention, there exists a small subgroup of patients with septic shock who develop progressive multi-organ failure. Seemingly refractory to conventional therapy, they exhibit a very high mortality. Such patients are often poorly represented in large clinical trials. Consequently, good evidence for effective treatment strategies is lacking. In this article, we describe a pragmatic, multi-faceted approach to managing patients with refractory septic shock based on our experience of toxin-mediated sepsis in a specialist referral centre. Many components of this strategy are inexpensive and widely accessible, and so may offer an opportunity to improve outcomes in these critically ill patients." @default.
- W2890665250 created "2018-09-27" @default.
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- W2890665250 date "2018-09-19" @default.
- W2890665250 modified "2023-10-14" @default.
- W2890665250 title "Refractory septic shock: our pragmatic approach" @default.
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- W2890665250 doi "https://doi.org/10.1186/s13054-018-2144-4" @default.
- W2890665250 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6145185" @default.
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