FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890675644> ?p ?o ?g. }

• W2890675644 abstract "e17029 Background: Vulvar cancer is a rare malignancy in women. During the past 30 years, large surveys of vulva cancer have not been performed in Japan. We therefore conducted a multicenter study to clarify the clinicopathological features of vulva cancer in Japan. Methods: In this multicenter retrospective cohort study, the clinical data of patients with vulva cancer were surveyed. The medical records of patients with vulvar cancer patients treated between 2001 and 2010 were retrospectively reviewed after obtaining approval from the Institutional Review Board of each institution. Survival analysis was performed using Kaplan-Meier curves. The effects of the clinical factors on overall survival were investigated using a Cox regression model. Results: A total of 1082 patients treated in 108 centers were studied. The median age was 72 years (range, 20 to 96). The disease stage was stage I in 415 patients (38.3%), stage II in 249 (23%), stage III in 255 (23.6%), and stage IV in 163 (15.1%) (FIGO 2009). The diagnosis was squamous cell carcinoma in 779 patients (72%), Paget’s disease in 158 (14.6%), adenocarcinoma in 63 (5.8%), and others in 82 (7.6%). Positive lymph nodes were found in 237 patients (21.9%). The median tumor diameter was 35 mm (range, 1 to 180). The 5-year overall survival was 86% in stage I, 74.7% in stage II, 48.2% in stage III, and 39.3% in stage IV (P < 0.001), and that according to histology was 63.9% in squamous cell carcinoma, 57.1% in adenocarcinoma, 79.7% in Paget’s disease, and 85.4% in others. The hazard ratio was 0.51 in patients with a histology of Paget’s disease or others (vs. squamous cell carcinoma or adenocarcinoma; P = 0.001; 95% CI, 0.35-0.75), 2.14 in patients with a the number of positive lymph nodes 2 or more (vs. 0 or 1; P < 0.001; 95% CI, 1.50-3.05), 2.10 in patients with a tumor diameter of ≥35mm (vs. < 35mm; P = 0.001; 95% CI, 1.36-3.25). Conclusions: Treatment outcomes in Japanese patients with vulvar cancer were similar to those reported previously. However, squamous-cell carcinoma, adenocarcinoma, positive lymph nodes, and bulky tumors were associated with poor outcomes. Multidisciplinary treatment might be required in patients with these characteristics. Clinical trial information: UMIN000017080." @default.
• W2890675644 created "2018-09-27" @default.
• W2890675644 creator A5001851469 @default.
• W2890675644 creator A5003859483 @default.
• W2890675644 creator A5012171799 @default.
• W2890675644 creator A5013565420 @default.
• W2890675644 creator A5013666054 @default.
• W2890675644 creator A5021999113 @default.
• W2890675644 creator A5038498441 @default.
• W2890675644 creator A5046191363 @default.
• W2890675644 creator A5056705916 @default.
• W2890675644 creator A5061710951 @default.
• W2890675644 creator A5065827694 @default.
• W2890675644 creator A5087124471 @default.
• W2890675644 creator A5087640271 @default.
• W2890675644 creator A5088282685 @default.
• W2890675644 date "2017-05-20" @default.
• W2890675644 modified "2023-09-26" @default.
• W2890675644 title "Investigation of the clinicopathological features of vulva cancer: A retrospective survey of the JGOG Net Work study." @default.
• W2890675644 doi "https://doi.org/10.1200/jco.2017.35.15_suppl.e17029" @default.
• W2890675644 hasPublicationYear "2017" @default.
• W2890675644 type Work @default.
• W2890675644 sameAs 2890675644 @default.
• W2890675644 citedByCount "0" @default.
• W2890675644 crossrefType "journal-article" @default.
• W2890675644 hasAuthorship W2890675644A5001851469 @default.
• W2890675644 hasAuthorship W2890675644A5003859483 @default.
• W2890675644 hasAuthorship W2890675644A5012171799 @default.
• W2890675644 hasAuthorship W2890675644A5013565420 @default.
• W2890675644 hasAuthorship W2890675644A5013666054 @default.
• W2890675644 hasAuthorship W2890675644A5021999113 @default.
• W2890675644 hasAuthorship W2890675644A5038498441 @default.
• W2890675644 hasAuthorship W2890675644A5046191363 @default.
• W2890675644 hasAuthorship W2890675644A5056705916 @default.
• W2890675644 hasAuthorship W2890675644A5061710951 @default.
• W2890675644 hasAuthorship W2890675644A5065827694 @default.
• W2890675644 hasAuthorship W2890675644A5087124471 @default.
• W2890675644 hasAuthorship W2890675644A5087640271 @default.
• W2890675644 hasAuthorship W2890675644A5088282685 @default.
• W2890675644 hasConcept C121608353 @default.
• W2890675644 hasConcept C126322002 @default.
• W2890675644 hasConcept C143998085 @default.
• W2890675644 hasConcept C16005928 @default.
• W2890675644 hasConcept C167135981 @default.
• W2890675644 hasConcept C2776316342 @default.
• W2890675644 hasConcept C2779399171 @default.
• W2890675644 hasConcept C2780370617 @default.
• W2890675644 hasConcept C29456083 @default.
• W2890675644 hasConcept C71924100 @default.
• W2890675644 hasConceptScore W2890675644C121608353 @default.
• W2890675644 hasConceptScore W2890675644C126322002 @default.
• W2890675644 hasConceptScore W2890675644C143998085 @default.
• W2890675644 hasConceptScore W2890675644C16005928 @default.
• W2890675644 hasConceptScore W2890675644C167135981 @default.
• W2890675644 hasConceptScore W2890675644C2776316342 @default.
• W2890675644 hasConceptScore W2890675644C2779399171 @default.
• W2890675644 hasConceptScore W2890675644C2780370617 @default.
• W2890675644 hasConceptScore W2890675644C29456083 @default.
• W2890675644 hasConceptScore W2890675644C71924100 @default.
• W2890675644 hasLocation W28906756441 @default.
• W2890675644 hasOpenAccess W2890675644 @default.
• W2890675644 hasPrimaryLocation W28906756441 @default.
• W2890675644 isParatext "false" @default.
• W2890675644 isRetracted "false" @default.
• W2890675644 magId "2890675644" @default.
• W2890675644 workType "article" @default.