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• W2890691009 startingPage "109" @default.
• W2890691009 abstract "Biologically safe Ti-based quaternary Ti-Nb-Zr-Si thin film metallic glass (TFMG) was fabricated by sputtering on Titanium alloy (Ti6Al4V or Ti alloy) substrates. A preliminary assessment regarding glass forming ability, thermal stability and corrosion behavior was performed. The amorphous nature of the film is evidenced from the X-ray Diffraction (XRD) and Transmission Electron Microscope (TEM) and Selected Area Electron Diffraction (SAED) patterns. Ion scattering spectroscopy (ISS) and X-ray Photoelectron Spectroscopy (XPS) were used to analyse the chemical composition of surface which indicated oxygen on the top surface of the film and confirms the presence of Ti, Nb, Si, Zr without any other impurities. The surface morphology of the film showed a smooth surface as observed from scanning electron microscope (SEM) and atomic force microscope (AFM) analysis. It is found that the TFMG can sustain in the body-fluid, exhibiting superior corrosion resistance and electrochemical stability than the bare titanium. The cytotoxicity studies with L929 fibroblast cells showed that coatings were graded as zero and non-cytotoxic in nature. No hemolysis was observed on the coated surface indicating a better hemocompatibility. Assay using SaOS-2 bone cells showed good growth on the coated surfaces. The calcium assay showed that the SaOS-2 cells grown and differentiated on the control (Tissue Culture Polystyrene) TCPS surface had the highest mineral level. Higher alkaline phosphatase activity is obtained in SaOS-2 osteoblast cell cultures on TFMG than the control." @default.
• W2890691009 created "2018-09-27" @default.
• W2890691009 creator A5007178745 @default.
• W2890691009 creator A5050043576 @default.
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• W2890691009 date "2019-01-01" @default.
• W2890691009 modified "2023-09-27" @default.
• W2890691009 title "Cytocompatibility assessment of Ti-Nb-Zr-Si thin film metallic glasses with enhanced osteoblast differentiation for biomedical applications" @default.
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• W2890691009 doi "https://doi.org/10.1016/j.colsurfb.2018.09.041" @default.
• W2890691009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30273871" @default.
• W2890691009 hasPublicationYear "2019" @default.
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