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- W2890693881 abstract "This review analyzed the published studies on the effects of thermal injury on gastrointestinal motility and mucosal damage. Our strategy was to integrate all available evidence to provide a complete review on the prokinetic properties of variable reagents and the potential clinical treatment of mucosal damage and gastrointestinal dysmotility after thermal injury. We classified the studies into two major groups: studies on gastrointestinal dysmotility and studies on mucosal damage. We also subclassified the studies into 3 parts: stomach, small intestine, and colon. This review shows evidence that ghrelin can recover burn-induced delay in gastric emptying and small intestinal transit, and can protect the gastric mucosa from burn-induced injury. Oxytocin and β-glucan reduced the serum inflammatory mediators, and histological change and mucosal damage indicators, but did not show evidence of having the ability to recover gastrointestinal motility. Using a combination of different reagents to protect the gastrointestinal mucosa against damage and to recover gastrointestinal motility is an alternative treatment for thermal injury." @default.
- W2890693881 created "2018-09-27" @default.
- W2890693881 creator A5012368089 @default.
- W2890693881 creator A5024549249 @default.
- W2890693881 creator A5091642561 @default.
- W2890693881 date "2018-12-01" @default.
- W2890693881 modified "2023-10-05" @default.
- W2890693881 title "Effects of burns on gut motor and mucosa functions" @default.
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- W2890693881 doi "https://doi.org/10.1016/j.npep.2018.09.004" @default.
- W2890693881 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30269923" @default.
- W2890693881 hasPublicationYear "2018" @default.
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