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- W2890697790 endingPage "112" @default.
- W2890697790 startingPage "112" @default.
- W2890697790 abstract "Candida albicans is a pleiomorphic fungus which co-exists with commensal bacteria in mucosal and skin sites of mammalian hosts. It is also a major co-isolated organism from polymicrobial systemic infections, with high potential for morbidity or mortality in immunocompromised patients. Traditionally, resident mucosal bacteria have been thought to antagonize C. albicans in its ability to colonize or cause infection. However, recent investigations have revealed synergistic relationships with certain bacterial species that colonize the same mucosal sites with C. albicans. Such relationships broaden the research landscape in pathogenesis but also contribute to clinical challenges in the prevention or treatment of mucosal candidiasis. This review sheds light on interactions of C. albicans and mucosal bacteria, with special emphasis on the effects of the resident bacterial microbiota on C. albicans physiology as they relate to its adaptation in mucosal sites as a commensal colonizer or as a pathogenic organism." @default.
- W2890697790 created "2018-09-27" @default.
- W2890697790 creator A5017105081 @default.
- W2890697790 creator A5072728089 @default.
- W2890697790 date "2018-09-18" @default.
- W2890697790 modified "2023-10-09" @default.
- W2890697790 title "Tipping the Balance: C. albicans Adaptation in Polymicrobial Environments" @default.
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- W2890697790 doi "https://doi.org/10.3390/jof4030112" @default.
- W2890697790 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6162738" @default.
- W2890697790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30231476" @default.
- W2890697790 hasPublicationYear "2018" @default.
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