Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890720103> ?p ?o ?g. }
- W2890720103 endingPage "33738" @default.
- W2890720103 startingPage "33734" @default.
- W2890720103 abstract "Sarcomatoid carcinoma is a rare malignancy characterized by a combination of epithelial and sarcoma or sarcoma-like components. In this study, we reported one case of pulmonary sarcomatoid carcinoma and evaluated the safety and efficacy of apatinib, a tyrosine kinase inhibitor selectively targeting vascular endothelial growth factor receptor 2, in treating this disease. The tumor mass was detected in the left lung of a 75-year-old man and showed positive immunostaining for cytokeratin (CK) 7, CK8, smooth muscle actin, CD31, and CD34. Next-generation sequencing analysis identified 4 mutations in NF1 (p.Q347Sfs*29), CDKN2A (p.G23V), ERBB3 (p.V104L), and TP53 (p.V157F) genes. The patient was given apatinib (250 mg) orally once per day. Sustained tumor regression was observed after apatinib treatment. There was no sever complication associated with apatinib therapy. In conclusion, apatinib-based targeted therapy may represent an important option for patients with sarcomatoid carcinoma." @default.
- W2890720103 created "2018-09-27" @default.
- W2890720103 creator A5000506603 @default.
- W2890720103 creator A5019018136 @default.
- W2890720103 creator A5035988809 @default.
- W2890720103 creator A5052180945 @default.
- W2890720103 creator A5054639323 @default.
- W2890720103 creator A5083735927 @default.
- W2890720103 date "2018-09-14" @default.
- W2890720103 modified "2023-10-10" @default.
- W2890720103 title "Apatinib-based targeted therapy against pulmonary sarcomatoid carcinoma: a case report and literature review" @default.
- W2890720103 cites W2015865703 @default.
- W2890720103 cites W2030511761 @default.
- W2890720103 cites W2031123636 @default.
- W2890720103 cites W2035693562 @default.
- W2890720103 cites W2092002101 @default.
- W2890720103 cites W2105950379 @default.
- W2890720103 cites W2113935263 @default.
- W2890720103 cites W2122441842 @default.
- W2890720103 cites W2141317943 @default.
- W2890720103 cites W2188914499 @default.
- W2890720103 cites W2192184960 @default.
- W2890720103 cites W2276228008 @default.
- W2890720103 cites W2328303366 @default.
- W2890720103 cites W2341548114 @default.
- W2890720103 cites W2355329030 @default.
- W2890720103 cites W2397028098 @default.
- W2890720103 cites W2504980652 @default.
- W2890720103 cites W2513558709 @default.
- W2890720103 cites W2522329661 @default.
- W2890720103 cites W2525918985 @default.
- W2890720103 cites W2565765232 @default.
- W2890720103 cites W2566627613 @default.
- W2890720103 cites W2568969101 @default.
- W2890720103 cites W2588466773 @default.
- W2890720103 cites W2596097530 @default.
- W2890720103 cites W2607037368 @default.
- W2890720103 cites W2618360530 @default.
- W2890720103 cites W2625668405 @default.
- W2890720103 cites W2673965378 @default.
- W2890720103 cites W2747382292 @default.
- W2890720103 cites W2749202673 @default.
- W2890720103 doi "https://doi.org/10.18632/oncotarget.25989" @default.
- W2890720103 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6154744" @default.
- W2890720103 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30263099" @default.
- W2890720103 hasPublicationYear "2018" @default.
- W2890720103 type Work @default.
- W2890720103 sameAs 2890720103 @default.
- W2890720103 citedByCount "10" @default.
- W2890720103 countsByYear W28907201032020 @default.
- W2890720103 countsByYear W28907201032021 @default.
- W2890720103 countsByYear W28907201032022 @default.
- W2890720103 countsByYear W28907201032023 @default.
- W2890720103 crossrefType "journal-article" @default.
- W2890720103 hasAuthorship W2890720103A5000506603 @default.
- W2890720103 hasAuthorship W2890720103A5019018136 @default.
- W2890720103 hasAuthorship W2890720103A5035988809 @default.
- W2890720103 hasAuthorship W2890720103A5052180945 @default.
- W2890720103 hasAuthorship W2890720103A5054639323 @default.
- W2890720103 hasAuthorship W2890720103A5083735927 @default.
- W2890720103 hasBestOaLocation W28907201031 @default.
- W2890720103 hasConcept C121608353 @default.
- W2890720103 hasConcept C126322002 @default.
- W2890720103 hasConcept C142724271 @default.
- W2890720103 hasConcept C143998085 @default.
- W2890720103 hasConcept C2777546739 @default.
- W2890720103 hasConcept C2778256501 @default.
- W2890720103 hasConcept C2778439243 @default.
- W2890720103 hasConcept C2778820342 @default.
- W2890720103 hasConcept C2778939058 @default.
- W2890720103 hasConcept C2779490328 @default.
- W2890720103 hasConcept C2780394083 @default.
- W2890720103 hasConcept C2780668389 @default.
- W2890720103 hasConcept C2780808757 @default.
- W2890720103 hasConcept C2781230642 @default.
- W2890720103 hasConcept C502942594 @default.
- W2890720103 hasConcept C71924100 @default.
- W2890720103 hasConceptScore W2890720103C121608353 @default.
- W2890720103 hasConceptScore W2890720103C126322002 @default.
- W2890720103 hasConceptScore W2890720103C142724271 @default.
- W2890720103 hasConceptScore W2890720103C143998085 @default.
- W2890720103 hasConceptScore W2890720103C2777546739 @default.
- W2890720103 hasConceptScore W2890720103C2778256501 @default.
- W2890720103 hasConceptScore W2890720103C2778439243 @default.
- W2890720103 hasConceptScore W2890720103C2778820342 @default.
- W2890720103 hasConceptScore W2890720103C2778939058 @default.
- W2890720103 hasConceptScore W2890720103C2779490328 @default.
- W2890720103 hasConceptScore W2890720103C2780394083 @default.
- W2890720103 hasConceptScore W2890720103C2780668389 @default.
- W2890720103 hasConceptScore W2890720103C2780808757 @default.
- W2890720103 hasConceptScore W2890720103C2781230642 @default.
- W2890720103 hasConceptScore W2890720103C502942594 @default.
- W2890720103 hasConceptScore W2890720103C71924100 @default.
- W2890720103 hasIssue "72" @default.
- W2890720103 hasLocation W28907201031 @default.
- W2890720103 hasLocation W28907201032 @default.
- W2890720103 hasLocation W28907201033 @default.
- W2890720103 hasLocation W28907201034 @default.