Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890728105> ?p ?o ?g. }
- W2890728105 abstract "In multiple sclerosis (MS), disability occurs as a result of complex interactions between glial cells and diverse components of acquired immunity. Microglial cells significantly contribute to disability progression by re-activating infiltrating lymphocytes, releasing neuro- and oligodendrocytotoxic mediators, inducing oxidative stress, and interfering with neuroplasticity. Recent research has emphasized the significance of meningeal B cell infiltrates in development of cognitive decline and disability. B cells are also involved in disability progression by way of production of neurotoxic antibodies directed against axoglial antigens. Among several immunological factors, neurofilament light chain antibodies, IgM-type oligoclonal bands, complement factor C3, and microglia-derived mediators stick out as potential reliable predictors of disability progression in MS patients. Better understanding of the interactions between innate immunity and neuroaxonal degeneration may result in development of novel and effective therapeutics for progressive types of MS." @default.
- W2890728105 created "2018-09-27" @default.
- W2890728105 creator A5038765962 @default.
- W2890728105 date "2018-01-01" @default.
- W2890728105 modified "2023-09-23" @default.
- W2890728105 title "Immunopathological factors associated with disability in multiple sclerosis" @default.
- W2890728105 cites W1846608835 @default.
- W2890728105 cites W1986173197 @default.
- W2890728105 cites W1989805933 @default.
- W2890728105 cites W1995353727 @default.
- W2890728105 cites W2004552736 @default.
- W2890728105 cites W2008423294 @default.
- W2890728105 cites W2015040716 @default.
- W2890728105 cites W2020869989 @default.
- W2890728105 cites W2039111082 @default.
- W2890728105 cites W2040078095 @default.
- W2890728105 cites W2046199264 @default.
- W2890728105 cites W2051274614 @default.
- W2890728105 cites W2056993431 @default.
- W2890728105 cites W2075180511 @default.
- W2890728105 cites W2075462921 @default.
- W2890728105 cites W2079146964 @default.
- W2890728105 cites W2082743251 @default.
- W2890728105 cites W2084887202 @default.
- W2890728105 cites W2087963310 @default.
- W2890728105 cites W2096757043 @default.
- W2890728105 cites W2108477230 @default.
- W2890728105 cites W2110632763 @default.
- W2890728105 cites W2111275943 @default.
- W2890728105 cites W2120307001 @default.
- W2890728105 cites W2125281412 @default.
- W2890728105 cites W2127176298 @default.
- W2890728105 cites W2128584287 @default.
- W2890728105 cites W2135607798 @default.
- W2890728105 cites W2138779588 @default.
- W2890728105 cites W2158169875 @default.
- W2890728105 cites W2159804314 @default.
- W2890728105 cites W2166899253 @default.
- W2890728105 cites W2208217844 @default.
- W2890728105 cites W2252299980 @default.
- W2890728105 cites W2314198668 @default.
- W2890728105 cites W2469466281 @default.
- W2890728105 cites W2513018262 @default.
- W2890728105 cites W2517566610 @default.
- W2890728105 cites W2519223478 @default.
- W2890728105 cites W2533333458 @default.
- W2890728105 cites W2534553832 @default.
- W2890728105 cites W2570694545 @default.
- W2890728105 cites W2587637294 @default.
- W2890728105 cites W2619378610 @default.
- W2890728105 cites W2621095463 @default.
- W2890728105 cites W2738927545 @default.
- W2890728105 cites W2751358423 @default.
- W2890728105 cites W2767227542 @default.
- W2890728105 cites W2790971608 @default.
- W2890728105 cites W2802931501 @default.
- W2890728105 doi "https://doi.org/10.29399/npa.23303" @default.
- W2890728105 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6278616" @default.
- W2890728105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30692851" @default.
- W2890728105 hasPublicationYear "2018" @default.
- W2890728105 type Work @default.
- W2890728105 sameAs 2890728105 @default.
- W2890728105 citedByCount "3" @default.
- W2890728105 countsByYear W28907281052021 @default.
- W2890728105 countsByYear W28907281052023 @default.
- W2890728105 crossrefType "journal-article" @default.
- W2890728105 hasAuthorship W2890728105A5038765962 @default.
- W2890728105 hasBestOaLocation W28907281052 @default.
- W2890728105 hasConcept C147483822 @default.
- W2890728105 hasConcept C15744967 @default.
- W2890728105 hasConcept C159654299 @default.
- W2890728105 hasConcept C169760540 @default.
- W2890728105 hasConcept C203014093 @default.
- W2890728105 hasConcept C2776914184 @default.
- W2890728105 hasConcept C2779830541 @default.
- W2890728105 hasConcept C2780640218 @default.
- W2890728105 hasConcept C71924100 @default.
- W2890728105 hasConcept C86803240 @default.
- W2890728105 hasConcept C87753298 @default.
- W2890728105 hasConceptScore W2890728105C147483822 @default.
- W2890728105 hasConceptScore W2890728105C15744967 @default.
- W2890728105 hasConceptScore W2890728105C159654299 @default.
- W2890728105 hasConceptScore W2890728105C169760540 @default.
- W2890728105 hasConceptScore W2890728105C203014093 @default.
- W2890728105 hasConceptScore W2890728105C2776914184 @default.
- W2890728105 hasConceptScore W2890728105C2779830541 @default.
- W2890728105 hasConceptScore W2890728105C2780640218 @default.
- W2890728105 hasConceptScore W2890728105C71924100 @default.
- W2890728105 hasConceptScore W2890728105C86803240 @default.
- W2890728105 hasConceptScore W2890728105C87753298 @default.
- W2890728105 hasLocation W28907281051 @default.
- W2890728105 hasLocation W28907281052 @default.
- W2890728105 hasLocation W28907281053 @default.
- W2890728105 hasLocation W28907281054 @default.
- W2890728105 hasOpenAccess W2890728105 @default.
- W2890728105 hasPrimaryLocation W28907281051 @default.
- W2890728105 hasRelatedWork W1837232209 @default.
- W2890728105 hasRelatedWork W2092427927 @default.
- W2890728105 hasRelatedWork W2286958858 @default.
- W2890728105 hasRelatedWork W2460405435 @default.