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• W2890731361 abstract "Oplopanax horridus , well-known as Devil’s club, is probably the most important ethnobotanical to most indigenous people living in the Pacific Northwest of North America. Compared with the long history of traditional use and widespread distribution in North America, the study of O. horridus is relatively limited. In the past decade, some exciting advances have been presented on the phytochemistry and pharmacological diversity and structure-activity relationship on anticancer effects of O. horridus . To date, no systematic review has been drafted on the recent advances of O. horridus . In this review, the different phytochemicals in O. horridus are compiled, including purified compounds and volatile components. Animal and in vitro studies are also described and discussed. Especially, the potential structural-activity relationship of polyynes on anticancer effects is highlighted. This review aimed to provide comprehensive and useful information for researching O. horridus and finding potential agents in drug discovery." @default.
• W2890731361 created "2018-09-27" @default.
• W2890731361 creator A5011287089 @default.
• W2890731361 creator A5020423570 @default.
• W2890731361 creator A5061500406 @default.
• W2890731361 creator A5075669369 @default.
• W2890731361 date "2018-09-13" @default.
• W2890731361 modified "2023-10-17" @default.
• W2890731361 title "<i>Oplopanax horridus</i>: Phytochemistry and Pharmacological Diversity and Structure-Activity Relationship on Anticancer Effects" @default.
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• W2890731361 doi "https://doi.org/10.1155/2018/9186926" @default.
• W2890731361 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6158975" @default.
• W2890731361 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30302120" @default.

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