FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2890734332> ?p ?o ?g. }

• W2890734332 abstract "Euphorbia supina (ES) has been widely used in folk medicine owing to its antibacterial, hemostatic, and anti-inflammatory properties. The aim of this study was to evaluate the antioxidant and skin-whitening effects of a 70% ethanol extract of ES.The aerial parts of ES plant were extracted with 70% ethanol. The viability of B16F10 cells was evaluated by MTT assay to determine the non-toxic doses for further experiments. The tyrosinase and cellular tyrosinase activities were then measured using an enzyme-substrate assay. In addition, the expression of whitening-related proteins was measured using western blot.The antioxidant activity of the ES samples increased in a dose-dependent manner, as confirmed by their radical scavenging activities in the 2,2-diphenyl-1-1-picrylhydrazyl and 2,2-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid) assays. The ES extract significantly reduced tyrosinase activity and melanin content in a dose-dependent manner. Furthermore, it decreased α-melanocyte stimulating hormone (MSH)-induced protein expression of tyrosinase and microphthalmia-associated transcription factor (MITF).Our results indicate that the ES extract attenuated α-MSH-stimulated melanin synthesis by modulating tyrosinase and MITF expression. Therefore, the ES extract could be a promising therapeutic agent to treat hyperpigmentation and as an ingredient for skin-whitening cosmetics." @default.
• W2890734332 created "2018-09-27" @default.
• W2890734332 creator A5007988614 @default.
• W2890734332 creator A5020090393 @default.
• W2890734332 creator A5022151896 @default.
• W2890734332 creator A5028506934 @default.
• W2890734332 creator A5038318775 @default.
• W2890734332 creator A5039325507 @default.
• W2890734332 creator A5058177669 @default.
• W2890734332 creator A5059888920 @default.
• W2890734332 creator A5063090175 @default.
• W2890734332 creator A5067088531 @default.
• W2890734332 creator A5069231267 @default.
• W2890734332 creator A5076141270 @default.
• W2890734332 creator A5077864741 @default.
• W2890734332 date "2018-09-17" @default.
• W2890734332 modified "2023-10-10" @default.
• W2890734332 title "Antioxidant and skin-whitening effects of aerial part of Euphorbia supina Raf. Extract" @default.
• W2890734332 cites W1523647733 @default.
• W2890734332 cites W1554730907 @default.
• W2890734332 cites W1853935617 @default.
• W2890734332 cites W1968873637 @default.
• W2890734332 cites W1979456082 @default.
• W2890734332 cites W1985729602 @default.
• W2890734332 cites W1988435244 @default.
• W2890734332 cites W1995566954 @default.
• W2890734332 cites W2006632364 @default.
• W2890734332 cites W2010684135 @default.
• W2890734332 cites W2012991711 @default.
• W2890734332 cites W2016331364 @default.
• W2890734332 cites W2031596649 @default.
• W2890734332 cites W2050360105 @default.
• W2890734332 cites W2061927865 @default.
• W2890734332 cites W2071772135 @default.
• W2890734332 cites W2093304762 @default.
• W2890734332 cites W2097985608 @default.
• W2890734332 cites W2114918609 @default.
• W2890734332 cites W2146627961 @default.
• W2890734332 cites W2148024485 @default.
• W2890734332 cites W2319076482 @default.
• W2890734332 cites W2467610418 @default.
• W2890734332 cites W2750522373 @default.
• W2890734332 cites W2951822083 @default.
• W2890734332 doi "https://doi.org/10.1186/s12906-018-2323-5" @default.
• W2890734332 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6142622" @default.
• W2890734332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30223806" @default.
• W2890734332 hasPublicationYear "2018" @default.
• W2890734332 type Work @default.
• W2890734332 sameAs 2890734332 @default.
• W2890734332 citedByCount "16" @default.
• W2890734332 countsByYear W28907343322019 @default.
• W2890734332 countsByYear W28907343322020 @default.
• W2890734332 countsByYear W28907343322021 @default.
• W2890734332 countsByYear W28907343322022 @default.
• W2890734332 countsByYear W28907343322023 @default.
• W2890734332 crossrefType "journal-article" @default.
• W2890734332 hasAuthorship W2890734332A5007988614 @default.
• W2890734332 hasAuthorship W2890734332A5020090393 @default.
• W2890734332 hasAuthorship W2890734332A5022151896 @default.
• W2890734332 hasAuthorship W2890734332A5028506934 @default.
• W2890734332 hasAuthorship W2890734332A5038318775 @default.
• W2890734332 hasAuthorship W2890734332A5039325507 @default.
• W2890734332 hasAuthorship W2890734332A5058177669 @default.
• W2890734332 hasAuthorship W2890734332A5059888920 @default.
• W2890734332 hasAuthorship W2890734332A5063090175 @default.
• W2890734332 hasAuthorship W2890734332A5067088531 @default.
• W2890734332 hasAuthorship W2890734332A5069231267 @default.
• W2890734332 hasAuthorship W2890734332A5076141270 @default.
• W2890734332 hasAuthorship W2890734332A5077864741 @default.
• W2890734332 hasBestOaLocation W28907343321 @default.
• W2890734332 hasConcept C104317684 @default.
• W2890734332 hasConcept C107538193 @default.
• W2890734332 hasConcept C142724271 @default.
• W2890734332 hasConcept C16005928 @default.
• W2890734332 hasConcept C177504595 @default.
• W2890734332 hasConcept C181199279 @default.
• W2890734332 hasConcept C185592680 @default.
• W2890734332 hasConcept C190283241 @default.
• W2890734332 hasConcept C2776415932 @default.
• W2890734332 hasConcept C2776677263 @default.
• W2890734332 hasConcept C2776728111 @default.
• W2890734332 hasConcept C2778004101 @default.
• W2890734332 hasConcept C2779078452 @default.
• W2890734332 hasConcept C2780532717 @default.
• W2890734332 hasConcept C2780783641 @default.
• W2890734332 hasConcept C2781424683 @default.
• W2890734332 hasConcept C2909381827 @default.
• W2890734332 hasConcept C45904493 @default.
• W2890734332 hasConcept C53227056 @default.
• W2890734332 hasConcept C55493867 @default.
• W2890734332 hasConcept C556039675 @default.
• W2890734332 hasConcept C71924100 @default.
• W2890734332 hasConcept C87554066 @default.
• W2890734332 hasConcept C98274493 @default.
• W2890734332 hasConceptScore W2890734332C104317684 @default.
• W2890734332 hasConceptScore W2890734332C107538193 @default.
• W2890734332 hasConceptScore W2890734332C142724271 @default.
• W2890734332 hasConceptScore W2890734332C16005928 @default.
• W2890734332 hasConceptScore W2890734332C177504595 @default.
• W2890734332 hasConceptScore W2890734332C181199279 @default.

• next