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- W2890735402 abstract "The estimation of Terizidone in pharmaceutical dosage form by using High Performance Thin Layer Chromatography was done using CAMAG HPTLC system. The separation was achieved using precoated silica gel 60 F 254 aluminium plates with mobile phase Toluene: n-Butanol 9:1 ml % v/v at wavelength 268 nm. The linearity range was found between 50-300 ng/ml-band having correlation coefficient 0.997. The recovery study of method showed the recovery between 99.3-101.6%. The LOD and LOQ values for method were 0.981 and 2.973 respectively. The R.S.D. of precision study was less than 2. The method parameters were validated as per ICH guidelines. The forced degradation studies revealed that the drug found stable in acidic, thermal and photo degradation. The LC-MS/MS study of degraded products gave the idea about the fragmentation patterns of degraded products.The developed method can be used for routine analysis of Terizidone and its formulations." @default.
- W2890735402 created "2018-09-27" @default.
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- W2890735402 date "2018-10-31" @default.
- W2890735402 modified "2023-09-24" @default.
- W2890735402 title "Development and validation of HPTLC and LC MS-MS method for estimation of Terizidone in pharmaceutical dosage form" @default.
- W2890735402 hasPublicationYear "2018" @default.
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